Results 61 to 70 of about 661,992 (346)

A procedure for the determination of proteolytic activity [PDF]

open access: yes, 1950
The difficulties introduced by the desire to maintain a constant pH during an enzyme-catalyzed hydrolysis of peptide-like substrates and at the same time to determine the extent of hydrolysis by an acid-base titration have been pointed out (1), but to ...
Iselin, Beat M., Niemann, Carl
core  

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Lyophilisation of influenza, rabies and Marburg lentiviral pseudotype viruses for the development and distribution of a neutralisation-assay based diagnostic kit [PDF]

open access: yes, 2014
Pseudotype viruses (PVs) are chimeric, replication-deficient virions that mimic wild-type virus entry mechanisms and can be safely employed in neutralisation assays, bypassing the need for high biosafety requirements and performing comparably to ...
Assar   +44 more
core   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Application of Potentiometric and Electrophoretic Measurements to Evaluate the Reversibility of Adsorption of Divalent Ions from a Solution on Titanium Dioxide

open access: yesMolecules
The adsorption of divalent ions on metal oxides is controlled by the pH of a solution. It is commonly assumed that this is a reversible process for pH changes. However, there are reports that the sorption of ions on oxides may not be reversible.
Wojciech Piasecki, Karolina Lament
doaj   +1 more source

The Use of Apremilast in Psoriasis: An Indian Perspective on Real-World Scenarios

open access: yesPsoriasis: Targets and Therapy, 2021
Murlidhar Rajagopalan,1 Sunil Dogra,2 Abir Saraswat,3 Sachin Varma,4 Pravin Banodkar5 1Department of Dermatology, Apollo Hospitals, Chennai, Tamilnadu, India; 2Department of Dermatology, Venereology & Leprology, PGIMER, Chandigarh, India; 3Indushree Skin
Rajagopalan M   +4 more
doaj  

Porphyra-334 Isolated from the Marine Algae Bangia atropurpurea: Conformational Performance for Energy Conversion

open access: yesMarine Drugs, 2014
Prophyra-334 (p-334) may play a role of energy transfer under an uncertain mechanism, and we speculate the possible model. Via 1D and 2D NMR experiments, it was simulated the correlation between dissociation and conformation of p-334.
Li-Fan Chuang   +2 more
doaj   +1 more source

Construction and Software Design for a Microcomputer Controlled pH/Ion Titrator [PDF]

open access: yes, 1984
The construction of an automated titration device is described. The major components include an Apple II+ Microcomputer and 8-bit parallel interface.
Mackey, James E.   +2 more
core   +2 more sources

Simulation of weak polyelectrolytes: A comparison between the constant pH and the reaction ensemble method

open access: yes, 2017
The reaction ensemble and the constant pH method are well-known chemical equilibrium approaches to simulate protonation and deprotonation reactions in classical molecular dynamics and Monte Carlo simulations.
Holm, Christian   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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