Results 81 to 90 of about 661,992 (346)

Challenges in medication titration in children with heart failure

JHLT Open
The management of pediatric heart failure and titration of oral medical therapies remains in its infancy. Burdened by a lack of understanding of the diverse pediatric heart failure etiologies, limitations in clinical trials, a lack of society guidelines,
Jessie Yester, MD, PhD, Deipanjan Nandi, MD, MSc   +1 more
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

THIOCYANATE ION-SELECTIVE PVC MEMBRANE ELECTRODE [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2010
A potentiometric selective sensor based on trinuclear chromium(III) complex as a novel ionophore for the thiocyanateselective electrode is reported. The sensor displays a near Nernstian slope of 57 ± 2 mV per decade, over a wide pH range 3 - 11.
Mihail Revenco, Mariana Martin, Waell Abu Dayyih   +2 more
doaj  

Controlling the Morphology of Aggregates of an Amphiphilic Synthetic Receptor through Host-Guest Interactions [PDF]

, 2006
A new amphiphilic receptor containing a macrocyclic anionic headgroup and a single alkyl chain was prepared through an efficient templated synthesis. The interdependence of the aggregation behavior and the host-guest chemistry was studied. In the absence
Chhabra, Anjali,, Figueiras Gómez, Sergio,, Liu, Jingyuan,, Otto, Sijbren,, Skepper, Jeremy N.,, Suksai, Chomchai,, Tuntulani, Thawatchai,   +6 more
core   +2 more sources

The titrating conditions in the potentiometric titration of zinc

BUNSEKI KAGAKU, 1964
硫酸酸性におけるフェロシアン化カリウムによる亜鉛の定量を,さまざまな滴定条件のもとに,白金-タングステン双金属電極を用いて電位差滴定を行ない,滴定に及ぼす諸影響を検討した.20℃では硫酸濃度,硫酸アンモニウム濃度によって終点の滴定量が異なるが,滴定溶液の容積100mlあたり硫酸濃度範囲0～0.05N,硫酸アンモニウム20gで一定の滴定速度のもとに行なうと,終点までの滴定量の再現性および電位差滴定曲線がともに良好で,終点における電位差変化が大きい.亜鉛濃度0.0025～0.0125Mの溶液を,滴定誤差約+1.5%で定量することができる.60℃ではすみやかに終点に達し,硫酸濃度,硫酸アンモニウム濃度,滴定時間の影響はより小さくなるが,終点における電位差変化が小さい.滴定誤差は約-1.2%である.
Saburo MIYAZAWA, Fumihiko OTSUKA
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Investigation of the Equilibrium Constant and Thermodynamic Properties of Borax Dissolution Using Titration Techniques

Dera Natung Government College Research Journal
This experiment uses the method of titrating saturated Borax aqueous solution with hydrochloric acid to determine the equilibrium constant of Borax as well as its enthalpy change, entropy change, and standard free energy of dissolution. Using this method,
Rimmo Loyi Lego, Lily Achumi
doaj   +1 more source

Carboxylic-acid-passivated metal oxide nanocrystals : ligand exchange characteristics of a new binding motif [PDF]

, 2015
Ligand exchange is central in the processing of inorganic nanocrystals (NCs) and requires understanding of surface chemistry. Studying sterically stabilized HfO2 and ZrO2 NCs using H-1 solution NMR and IR spectroscopy as well as elemental analysis, this ...
Anderson, Anderson, Boettcher, Caldwell, Cros-Gagneux, De Roo, De Roo, Dierick, Fritzinger, Green, Green, Hassinen, Hens, Huang, Jasieniak, Morris-Cohen, Nel, Owen, Schrauben, Valdez, Valdez, Zherebetskyy   +21 more
core   +1 more source

High-Precision Isothermal Titration Calorimetry with Automated Peak Shape Analysis

Analytical Chemistry, 2012
Isothermal titration calorimetry (ITC) is a powerful classical method that enables researchers in many fields to study the thermodynamics of molecular interactions. Primary ITC data comprise the temporal evolution of differential power reporting the heat
S. Keller, Carolyn Vargas, Huaying Zhao, G. Piszczek, C. Brautigam, P. Schuck   +5 more
semanticscholar   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source