Results 51 to 60 of about 6,703 (188)

Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View

Journal of Toxicology, Volume 2012, Issue 1, 2012., 2012
Nervous system of Periplaneta americana cockroach is used in a wide range of pharmacological studies, including electrophysiological techniques. This paper presents its role as a preparation in the development of toxinological studies in the following electrophysiological methods: double‐oil‐gap technique on isolated giant axon, patch‐clamp on DUM ...
Maria Stankiewicz, Marcin Dąbrowski, Maria Elena de Lima, Yonghua Ji   +3 more
wiley   +1 more source

Scorpion envenomation in Brazil: Current scenario and perspectives for containing an increasing health problem.

PLoS Neglected Tropical Diseases, 2023
Opportunistic scorpion species can colonize urban environments, establishing high-density communities that enhance the chances of human accidents.
Clara Guerra-Duarte, Rafael Saavedra-Langer, Alessandra Matavel, Barbara B R Oliveira-Mendes, Carlos Chavez-Olortegui, Ana Luiza Bittencourt Paiva   +5 more
doaj   +1 more source

Scorpion Venom and the Inflammatory Response

Mediators of Inflammation, Volume 2010, Issue 1, 2010., 2010
Scorpion venoms consist of a complex of several toxins that exhibit a wide range of biological properties and actions, as well as chemical compositions, toxicity, and pharmacokinetic and pharmacodynamic characteristics. These venoms are associated with high morbility and mortality, especially among children. Victims of envenoming by a scorpion suffer a
Vera L. Petricevich, Fulvio D′Acquisto
wiley   +1 more source

Second record of Tityus bahiensis (Scorpiones, Buthidae) from Venezuela: epidemiological implications

Journal of Venomous Animals and Toxins including Tropical Diseases, 2008
This work reports the second record of the scorpion Tityus bahiensis Perty from Venezuela. The specimen was found alive in a wardrobe at a hotel resort in Margarita Island, northeastern Venezuela.
L. De Sousa, A. Borges, J. Manzanilla, I. Biondi, E. Avellaneda   +4 more
doaj   +1 more source

Genetic and toxinological divergence among populations of Tityus trivittatus Kraepelin, 1898 (Scorpiones: Buthidae) inhabiting Paraguay and Argentina [PDF]

, 2020
Autor de correspondencia: borges.adolfo@gmail.comEnvenoming by scorpions in genus Tityus is a public health problem in Tropical America. One of the most medically significant species is Tityus trivittatus, which is known to occur from southwest Brazil to
Borges Strauss, Adolfo, Chávez Olórtegui, Carlos, Coronel, Cathia Cecilia, de Almeida Lima, Sabrina, de Roodt, Adolfo R., Díaz, Cecilia, Graham, Matthew R., Kalapothakis, Evanguedes, Lomonte, Bruno, Rojas de Arias, Gladys Antonieta   +9 more
core   +1 more source

Immunomodulatory Effects of the Tityus serrulatus Venom on Murine Macrophage Functions in Vitro

Mediators of Inflammation, Volume 2005, Issue 1, Page 39-49, 2005., 2005
Tityus serrulatus scorpion venom (TSV) consists of a very complex mixture of molecules and demonstrates significant immunomodulatory activities capable of stimulating immune functions in vivo. The purpose of this study was to compare the crude TSV with fractionated toxins extracted from this venom in order to determine which toxin(s) presented ...
Vera L. Petricevich, Ivo Lebrun
wiley   +1 more source

Scorpions from the primeval subgenus Archaeotityus produce putative homologs of Tityus serrulatus toxins active on voltage-gated sodium channels

Journal of Venomous Animals and Toxins including Tropical Diseases, 2012
It has been proposed that the subgenus Archaeotityus comprises the most ancient species group within the medically important scorpion genus Tityus. cDNA encoding sodium-channel active toxins from the type species of this subgenus, Tityus clathratus ...
A Borges, MJ Jowers, S Bónoli, L De Sousa   +3 more
doaj   +1 more source

Effect of Tityus serrulatus venom on cytokine production and the activity of murine macrophages

Mediators of Inflammation, Volume 11, Issue 1, Page 23-31, 2002., 2002
The purpose of this study was to investigate the effects of Tityus serrulatus venom (TSV) on murine peritoneal macrophages evaluated in terms of activation. The effects of crude TSV were analysed by detection of cytokines, oxygen intermediate metabolites (H2O2) and nitric oxide (NO) in supernatants of peritoneal macrophages.
Vera L. Petricevich
wiley   +1 more source

Functional Properties and Toxin Pharmacology of a Dorsal Root Ganglion Sodium Channel Viewed through its Voltage Sensors [PDF]

, 2013
The voltage-activated sodium (Nav) channel Nav1.9 is expressed in dorsal root ganglion (DRG) neurons where it is believed to play an important role in nociception.
Bean, Bruce Palmer, Bosmans, Frank, Martin-Eauclaire, Marie-France, Puopolo, Michelino, Swartz, Kenton J.   +4 more
core   +1 more source

Genotoxicity evaluation induced by Tityus serrulatus scorpion venom in mice

Toxicon, 2017
Tityus serrulatus is the scorpion associated with the most severe cases of scorpion envenoming in Brazil. However, there are no studies reporting the genotoxic effects of this venom in natural or experimental envenomations. It is well known that DNA-damage responses are providing opportunities for improving disease detection and management.
Nathalia Coral Galvani, Thais Ceresér Vilela, Angelino Chitoma Domingos, Mírian Ívens Fagundes, Luiza Macarini Bosa, Indiani Conti Della Vechia, Rahisa Scussel, Márcia Pereira, Bethina Trevisol Steiner, Adriani Paganini Damiani, Carlos Chávez-Olórtegui, Vanessa Moraes De Andrade, Ricardo Andrez Machado de Ávila   +12 more
openaire   +2 more sources