Results 31 to 40 of about 30,377 (206)

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Data‐Driven Feedback Identifies Focused Ultrasound Exposure Regimens for Improved Nanotheranostic Targeting of the Brain

Advanced Science, EarlyView.
Machine learning models predict in real time the onset of harmful microbubble collapse during microbubble‐enhanced focused ultrasound (MB‐FUS) and enable dynamic adjustment of sonication to prevent cavitation‐induced damage. This predictive control expands the safe operating window for bloodbrain barrier opening, enhancing nanoparticle delivery and ...
Hohyun Lee, Victor Menezes, Shiqin Zeng, Chulyong Kim, Cynthia M. Baseman, Jae Hyun Kim, Samhita Padmanabhan, Pranav Premdas, Naima Djeddar, Anton Bryksin, Nikhil Pandey, Pavlos Anastasiadis, Anthony J. Kim, Tobey J. MacDonald, Chetan Bettegowda, Graeme F. Woodworth, Felix J. Herrmann, Costas Arvanitis   +17 more
wiley   +1 more source

Multi‐View Biomedical Foundation Models for Molecule‐Target and Property Prediction

Advanced Science, EarlyView.
Molecular foundation models can provide accurate predictions for a large set of downstream tasks. We develop MMELON, an approach that integrates pre‐trained graph, image, and text foundation models and validate our multi‐view model on over 120 tasks, including GPCR binding.
Parthasarathy Suryanarayanan, Yunguang Qiu, Shreyans Sethi, Diwakar Mahajan, Hongyang Li, Yuxin Yang, Elif Eyigoz, Aldo Guzmán‐Sáenz, Daniel E. Platt, Timothy H. Rumbell, Kenney Ng, Sanjoy Dey, Myson Burch, Bum Chul Kwon, Pablo Meyer, Feixiong Cheng, Jianying Hu, Joseph A. Morrone   +17 more
wiley   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

A review of gear housing dynamics and acoustics literature [PDF]

A review of the available literature on gear housing vibration and noise reduction is presented. Analytical and experimental methodologies used for bearing dynamics, housing vibration and noise, mounts and suspensions, and the overall geared and housing ...
Lim, Teik Chin, Singh, Rajendra
core   +1 more source

Electrode Engineering for High‐Durability Variable‐Emissivity Devices Based on Reversible Copper Electrodeposition

Advanced Science, EarlyView.
An Ir‐based reversible copper electrodeposition variable‐emissivity device achieved over 8000 cycles with just 11% radiative temperature variation decay. This stability stems from Ir's inherent inertness, high conductivity, and strength, which collectively suppress cracking and corrosion.
Runyun He, Tianwen Liu, Liqiang Zhang, Tuoyu Liu, Dan Tang, Wenxia Zhang, Jundong Tao, Tingting Shi, Yijing Song, Haifeng Cheng, Yao Zhang, Dongqing Liu   +11 more
wiley   +1 more source

From Physics to Economics: An Econometric Example Using Maximum Relative Entropy

, 2009
Econophysics, is based on the premise that some ideas and methods from physics can be applied to economic situations. We intend to show in this paper how a physics concept such as entropy can be applied to an economic problem. In so doing, we demonstrate
Adom Giffin, Caticha, Cover, Giffin, Jaynes, Jaynes, Owen, Shannon, Shore, Skilling   +9 more
core   +1 more source

Beyond Traditional RAFT Polymerization: Emerging Strategies and Future Perspectives; A Third Update

Advanced Science, EarlyView.
This review explores recent advances in the past five years for non‐traditional RAFT polymerization, focusing on new activation strategies, sustainable depolymerization, and integration with automated and AI‐driven synthesis. Together, these innovations advance polymer chemistry and reveal how the pieces of the non‐traditional RAFT puzzle are steadily ...
Vianna F. Jafari, James L. Grace, Jiajia Li, Joji Tanaka, Glen R. Jones, Athina Anastasaki, Wei You, Jian Zhu, Masami Kamigaito, Cyrille Boyer, Greg G. Qiao   +10 more
wiley   +1 more source

Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity

Advanced Science, EarlyView.
Most rare diseases are caused by genetic mutations. Prime editing (PE) has emerged as a versatile tool capable of inducing diverse mutations without generating DNA double‐strand breaks. Despite its significant clinical potential, PE faces limitations in terms of efficiency and scalability.
Jihyeon Yu, Ju‐Chan Park, Heesoo Uhm, Yong‐Woo Kim, Hyeon Woo Im, Sangsu Bae   +5 more
wiley   +1 more source

3D‐Printed Aerogel Metamaterials with Multiple Heterogeneous Interfaces Enables Integrated Control of Microwave Field, Acoustic Field, and Thermal Field

Advanced Science, EarlyView.
The Direct‐Ink‐Writing (DIW) 3D‐printed aramid nanofibers (ANF)/carbon nanotubes (CNT)/liquid metal (LM) aerogel metamaterial demonstrates an effective and lightweight strategy to achieve polarization insensitive & ultra‐wideband microwave absorption from 2.65‐18 GHz, broadband noise reduction effect in the 2800‐6400 Hz and thermal suppression ...
Yijie Liu, Kokila Khanal, Weimeng Chu, Sreekanth Ginnaram, Yijing Zhao, Chunlin Jia, Udeshwari Jamwal, Jiaqi Tao, Lvtong Duan, Wentao Yan, Yong Yang   +10 more
wiley   +1 more source