Results 81 to 90 of about 18,054 (205)

Time-motion analysis and effort-pause relationship in taekwondo combats: a comparison of competitive levels

Revista Brasileira de Cineantropometria e Desempenho Humano, 2016
To improve the combat sports training processes, the knowledge of effort:pause (E:P) ratio and of the high intensity:low intensity (HI:LI) relationship may be useful. However, no studies have investigated these aspects in taekwondo (TKD) official matches
Fabrício Boscolo Del Vecchio, Bruno Antunez, Charles Bartel   +2 more
doaj   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

PSIKOLOGI KOGNITIF SEBAGAI DASAR PENGEMBANGAN TES KEMAMPUAN DASAR MEMBACA BIDANG SAINS

Jurnal Penelitian dan Evaluasi Pendidikan, 2013
Penelitian ini bertujuan untuk: (1) menguji psikologi kognitif sebagai dasar pengembangan tes kemampuan dasar (TKD) membaca sains; (2) menentukan karakteristik TKD membaca sains yang dikembangkan; (3) menentukan kriteria penilaian dan cara ...
Ani Rusilowati
doaj  

Increased Functional Mobility in Healthy Elderly Individuals After Six Months of Adapted Taekwondo Practice

Applied Sciences
Age-related muscle mass and force reduction may ultimately pave the way for loss of independence, reduced quality of life (QoL) and increased falls, which represents one of the primary causes of hospitalization and death among the elderly.
Carmen Giulia Lia, Francesca Greco, Mario Antonio Muscari, Marco Spadafora, Salvatore Chiodo, Gian Pietro Emerenziani, Federico Quinzi   +6 more
doaj   +1 more source

Relic density and PAMELA events in a heavy wino dark matter model with Sommerfeld effect

, 2012
In a wino LSP scenario the annihilation cross section of winos gravitationally bound in galaxies can be boosted by a Sommerfeld enhancement factor which arises due to the ladder of exchanged W bosons between the initial states.
Mohanty, Subhendra, Rao, Soumya, Roy, D. P.   +2 more
core   +1 more source

Identification and Functional Characterization of Novel and Recurrent NTRK1 Variants in Chinese Families With Congenital Insensitivity to Pain With Anhidrosis: A Combined Clinical, Genetic, and Functional Study

European Journal of Neurology, Volume 33, Issue 5, May 2026.
This study investigates four Chinese families with congenital insensitivity to pain with anhidrosis (CIPA). Through next‐generation sequencing, we identified seven NTRK1 variants, including two novel mutations. Functional characterization of five identified missense and indel variants revealed distinct disruptions in the NGF‐TrkA pathway, ranging from ...
Yaqiong Ren, Yue Cao, Fangfang Cheng, Jin Dai, Yuan Zhang, Xinxin Wang, Jiali Chen, Lijun Zhou, Xiaoxiang Song, Hongying Wang   +9 more
wiley   +1 more source

Diffuse gamma-ray background and cosmic-ray positrons from annihilating dark matter

, 2009
We study the annihilating dark matter contribution to the extra-galactic diffuse gamma-ray background spectrum, motivated by the recent observations of cosmic-ray positron/electron anomalies.
A. Burkert, Kazunori Kohri, Kazunori Nakayama, Masahiro Kawasaki, S. Desai, V. R. Eke   +5 more
core   +1 more source

Data‐Driven Design and Fabrication of Heat‐Resistant, Ultrastrong, Lightweight Aluminum‐Based Entropy Alloy by Additive Manufacturing

Advanced Science, Volume 13, Issue 19, 2 April 2026.
A data‐driven strategy integrating quantum machine learning (QML) and high‐throughput computing overcomes hot‐cracking limitation to design a novel lightweight aluminum‐based entropy alloy for additive manufacturing. The fabrication transforms brittle intermetallics into deformable hierarchical nanostructures, yielding ultrastrong strength (>1 GPa) and
Enmao Wang, Chao Ding, Danyang Zhou, Chenjin Xu, Swee Leong Sing, Jianzhong Jiang, Huibin Wu   +6 more
wiley   +1 more source

Activating FLT3 mutants show distinct gain-of-function phenotypes in vitro and a characteristic signaling pathway profile associated with prognosis in acute myeloid leukemia.

PLoS ONE, 2014
About 30% of patients with acute myeloid leukemia (AML) harbour mutations of the receptor tyrosine kinase FLT3, mostly internal tandem duplications (ITD) and point mutations of the second tyrosine kinase domain (TKD).
Hanna Janke, Friederike Pastore, Daniela Schumacher, Tobias Herold, Karl-Peter Hopfner, Stephanie Schneider, Wolfgang E Berdel, Thomas Büchner, Bernhard J Woermann, Marion Subklewe, Stefan K Bohlander, Wolfgang Hiddemann, Karsten Spiekermann, Harald Polzer   +13 more
doaj   +1 more source

Evolution of the phase-space density and the Jeans scale for dark matter derived from the Vlasov-Einstein equation

, 2013
We discuss solutions of Vlasov-Einstein equation for collisionless dark matter particles in the context of a flat Friedmann universe. We show that, after decoupling from the primordial plasma, the dark matter phase-space density indicator Q remains ...
Fabris, Júlio C., Pacheco, José A. de Freitas, Piattella, Oliver F., Rodrigues, Davi C.   +3 more
core   +1 more source