Results 91 to 100 of about 143,294 (307)

TLC determination of some flavanones in the buds of different genus Populus species and hybrids

open access: yesActa Pharmaceutica, 2018
Flavonoids in the buds of eight Populus species and hybrids were detected and compared with the aid of an optimized TLC method. Separation of 17 flavonoid aglycones belonging to different groups, namely, flavones, flavonols, flavanones and flavanonols ...
Pobłocka-Olech Loretta   +2 more
doaj   +1 more source

Fatty acid profile and effect of fish fermented silage on digestive enzymes in Labeo rohita

open access: yesBioscience Journal, 2017
Due to inconsistency in demand and supply of fishmeal there is immense need of alternate protein sources. Present project was therefore designed to replace costly fishmeal (FM) with low-priced fermented fish silage (FFS) in fish feed.
Muhammad Sultan Haider   +5 more
doaj   +1 more source

One‐Pot Synthesis of a Small Synthetic Ligand for Antibody Purification

open access: yesBiotechnology and Bioengineering, EarlyView.
One‐pot liquid‐phase synthesis of the synthetic ligand B1Al2A2 enables controllable ligand density and efficient capture of IgG and IgY with high recovery and purity, streamlining small‐ligand affinity purification workflows. ABSTRACT The development of synthetic affinity ligands offers a cost‐effective alternative to traditional biological ligands ...
Carolina Mota Natal   +8 more
wiley   +1 more source

Discovery of CRBN‐based molecular glue degraders targeting WIZ transcription factor

open access: yesBulletin of the Korean Chemical Society, EarlyView.
This work reports the discovery of 9l, a novel cereblon‐based molecular glue degrader which targets the WIZ transcription factor. Compound 9l facilitates WIZ‐CRBN ternary complex formation to degrade WIZ, subsequently inducing γ‐globin expression in HUDEP‐2 cells and highlighting its potential as a sickle cell disease therapy.
Tae‐Jun Kim   +8 more
wiley   +1 more source

Development of method of qualitative analysis of bird cherry fruit for inclusion in the monograph of state pharmacopoeia of Ukraine

open access: yesAnnals of Mechnikov's Institute, 2020
Introduction.Bird cherryPadusaviumMill, Rosaceae,is widespread in Ukraine, especially in forests and forest-steppe areas. Bird cherry fruits have long been used in medicine and is a valuable medicinal raw materials. They stated to posess astringent, anti-
L Lenchyk   +3 more
doaj  

Exploration of structure–activity relationship of 2,4‐diaminopyrimidine derivatives as hematopoietic progenitor kinase 1 inhibitors

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Targeting HPK1 is a promising strategy to restore T‐cell anti‐tumor immunity. We report the design and synthesis of novel 2,4‐diaminopyrimidine derivatives, focusing on systematic structure–activity relationship (SAR) analysis These findings identify key structural features for potent HPK1 inhibition, facilitating the discovery of next‐generation ...
Heechan Shin   +3 more
wiley   +1 more source

El TLC entre EEUU y la UE: incidencias en el poder de negociación estadounidense a partir de las declaraciones de Edward Snowden sobre el espionaje en el periodo entre febrero 2013 y marzo 2014

open access: yes, 2017
En su discurso de Estado de Unión de 2013, el presidente estadounidense, Barack Obama, anunció su decisión de negociar un tratado de libre comercio (TLC) con la Unión Europea.
Crespo Pazmiño, Daniel Fernando
core   +1 more source

Assessment and Control of Organic Impurities in Medicinal Products: A Review

open access: yesРегуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. The determination of impurities is a key requirement for the quality assessment of medicines because impurities can significantly impact the quality and therapeutic effectiveness.
O. A. Matveeva   +2 more
doaj   +1 more source

Methyl on the Bridge: 2‐Methyl Propellane as Precursor for 1,3‐Substituted 2‐Methylated Bicyclo[1.1.1]Pentanes

open access: yesChemistry – A European Journal, EarlyView.
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve   +4 more
wiley   +1 more source

STUDY OF CHROMATOGRAPHIC FINGERPRINT OF FLAVONOID COMPOUNDS OF THE BUR-MARIGOLD HERB

open access: yesScientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2021
The main aim of this work was to determine the possibility of reliable identification of phenolic compounds, in particular flavonoids, specific for very popular type of medicinal plant material Bidens (B. tripartita, B. frondosa, B.
ELINA E. KOTOVA   +2 more
doaj  

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