Geminal dimethoxyethers react with pyrrolic nucleophiles in an efficient and clean reaction under anhydrous, mild conditions, which contrasts with the reactivity of the respective carbonyl compounds. Polymerization is effectively inhibited, providing access to dipyrromethanes, porphyrins, and calix[4]pyrroles that are easily purified.
Janos Wasternack +10 more
wiley +1 more source
Development of a radio thin-layer chromatography scanner: Design and qualification. [PDF]
Chivato Martín-Falquina T +3 more
europepmc +1 more source
Pulmonary hypertension associated with COPD: exploring the complex spectrum of an unmet clinical challenge. [PDF]
Riou M, Beurnier A, Montani D.
europepmc +1 more source
ABSTRACT This study aimed to quantify the cannibal‐prey size relationship using morphometric regression models and to establish an effective size‐grading strategy to prevent cannibalism. A total of 15,000 juveniles at 73 days post‐hatching (DPH) were reared in a circular tank (approximately 12 tons) operated under a flow‐through seawater system at 26.0
Moon‐Soo Boo, Chi‐Hoon Lee
wiley +1 more source
Gene signature linked to inhaled corticosteroid-induced lung function improvement in COPD: insights from the GLUCOLD Study. [PDF]
Zhang J +6 more
europepmc +1 more source
Inter‐and Intramolecular (4+3) Cycloadditions With Epoxy Allylsilanes as Dienophiles
Methylenated cycloheptanoids are synthesized by formal (4+3) cycloadditions of dienes with epoxy allylsilanes as dienophiles in the presence of catalytic amounts of TESOTf. Intermolecular and intramolecular (4+3) cycloadditions with dienes including furans, cyclopentadiene, pyrroles, thiophenes, and benzenes proceeded to provide polycyclic adducts in ...
Qin Han Teo +3 more
wiley +1 more source
Interstitial lung disease in systemic sclerosis-a retrospective cross-sectional study in Taiwan. [PDF]
Liu CW +8 more
europepmc +1 more source
Contrasting Global and Patient‐Specific Regression Models via a Neural Network Representation
ABSTRACT When developing clinical prediction models, it can be challenging to balance between global models that are valid for all patients and personalized models tailored to individuals or potentially unknown subgroups. To aid such decisions, we propose a diagnostic tool for contrasting global regression models and patient‐specific (local) regression
Max Behrens +7 more
wiley +1 more source
Challenging the Macrocycle Paradigm: Four-Arm, High-Denticity Acyclic Chelators for Radiopharmaceuticals Incorporating Actinium and Lanthanides. [PDF]
Fernández-Pavón D +10 more
europepmc +1 more source
ABSTRACT Alzheimer's disease (AD) is a fatal neurodegenerative disorder that affects cognition, memory, and behavior. Such a disease is considered the most common cause of dementia and affects a large portion of the elderly population worldwide. Currently, cholinesterase inhibitors are used to reduce the symptoms and rate of progression of this disease.
Susiany Pereira Lopes +6 more
wiley +1 more source

