Results 41 to 50 of about 143,294 (307)

A Lipid‐Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells

Angewandte Chemie, EarlyView.
A lipid conjugation strategy anchors a manganese Salen complex within phospholipid membranes, yielding stable, catalytically active liposomes. These lipid–metal assemblies efficiently degrade reactive oxygen species (ROS) and enable intracellular redox control in steatotic HepaRG cells, offering a precise route to biomimetic antioxidant design ...
Olav Vestrheim, Huichao Zhao, Anders Bodholt Nielsen, Nino Wili, Niels Chr. Nielsen, Joseph A. Lyons, Rajeshwar Prosad Mookerjee, Brigitte Städler   +7 more
wiley   +2 more sources

A New Topology of Multi-Input Bidirectional DC-DC Converters for Hybrid Energy Storage Systems

Energies
A new topology of multi-input bidirectional DC-DC converters is proposed in this paper. The converter has a boost behavior, i.e., the output voltage is higher than the sum of the input voltages. This family of converters is particularly suited for hybrid
Simone Cosso, Alessandro Benevieri, Mario Marchesoni, Massimiliano Passalacqua, Luis Vaccaro, Paolo Pozzobon   +5 more
doaj   +1 more source

Komposisi Pigmen pada Ulva sp., Padina australis dan Hypnea sp. dari Pantai Tablolong Provinsi Nusa Tenggara Timur

Jurnal Kelautan Tropis, 2020
Indonesia has marine biological natural resources consisting of fish, seaweed, crabs and shrimp which are very potential. The purpose of this study was to determine the composition of pigments in Ulva sp (Chlorophyta), Padina australis (Paeophyta) and ...
Martice Desi Pesang, James Ngginak, Alfred Gasper Onisimus Kase, Coni Lisandra Balle Bisilissin   +3 more
doaj   +1 more source

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source

Chelator‐Free Radiometal Labeling Inside Engineered Affibodies

Angewandte Chemie, EarlyView.
Affibodies are compact and robust three‑helix binders used in imaging and therapy. Engineering a triple‑cysteine motif into their core enables chelator‑free binding of important radiometals, like Bi(III), Pb(II), In(III), and Ga(III) with rapid uptake and exceptional stability.
Lani J. Davies, Upamali Somathilake, Santhanalaxmi Kumaresan, Frank Bruchertseifer, Alfred Morgenstern, Sarah Spreckelmeyer, Christoph Nitsche   +6 more
wiley   +2 more sources

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

The effect of Buddhist pirith chanting and Western pop music on growth performance of “Pranajeewa”, Codariocalyx motorius (Houtt.) H. Ohashi

Ceylon Journal of Science, 2018
Response of Codariocalyx motorius to Western pop music and Pirith chanting was examined by conducting an experiment with three months old C. motorius saplings, kept in a sound proof confined chamber.
D.S.P. Munasinghe, S.R. Weerakoon, S. Somaratne   +2 more
doaj   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

Impacto del TLC en Bogotá-Cundinamarca La cadena de industrias gráficas [PDF]

, 2007
Gestión del conocimientoEste informe sobre el impacto del TLC en Bogotá-Cundinamarca La cadena de cuero-calzado incluye el rezago frente a la globalización, el impacto del TLC en la economía regional y el TLC y la cadena de industrias gráficas ...
Fedesarrollo
core  

AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling

Advanced Science, EarlyView.
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi, Minying Low, Peng Xiu, Kresten Lindorff‐Larsen, Yong Wang   +4 more
wiley   +1 more source