Results 1 to 10 of about 2,974 (158)

The CNS Meninges and the Synovial Joint: Parallel Immunological Structures in Autoimmune Disease. [PDF]

Bioessays
The meninges and synovium share multiple functional and structural characteristics and act as specialized immunological barriers. In MS and RA, both can host tertiary lymphoid organs (TLOs) and CD4+ Tph cells. We highlight how these features sustain compartmentalized inflammation and explore a possible role for EBV in their formation and persistence ...
Fazazi MR, Rangachari M.
europepmc   +2 more sources

Deletion of the Candida albicans TLO gene family using CRISPR-Cas9 mutagenesis allows characterisation of functional differences in α-, β- and γ- TLO gene function. [PDF]

PLoS Genetics, 2023
The Candida albicans genome contains between ten and fifteen distinct TLO genes that all encode a Med2 subunit of Mediator. In order to investigate the biological role of Med2/Tlo in C.
Jessica Fletcher, James O'Connor-Moneley, Dean Frawley, Peter R Flanagan, Leenah Alaalm, Pilar Menendez-Manjon, Samuel Vega Estevez, Shane Hendricks, Andrew L Woodruff, Alessia Buscaino, Matthew Z Anderson, Derek J Sullivan, Gary P Moran   +12 more
doaj   +2 more sources

A Case of Refractory Childhood Glaucoma Associated With Sturge-Weber Syndrome Treated With Baerveldt Glaucoma Implant. [PDF]

Case Rep Ophthalmol Med
We reported the clinical course of refractory childhood glaucoma associated with Sturge–Weber syndrome (SWS) treated with Baerveldt glaucoma implant (BGI). The patient was a 14‐year‐old male diagnosed with SWS after birth. He had previously undergone four trabeculotomies for glaucoma and vitrectomy for submacular hemorrhage from a diffuse choroidal ...
Imamura W, Matsuda A, Hirota A, Kuroda K, Kitagawa Y, Saeki T, Kambe T, Yamamoto S, Yamagami S.   +8 more
europepmc   +2 more sources

Artery Tertiary Lymphoid Organs Form Neuroimmune Cardiovascular Interfaces in Atherosclerosis. [PDF]

Immunol Rev
ABSTRACT Arterial walls of large‐ and intermediate‐sized arteries consist of three layers, that is, the intima, the media, and the adventitia. Under physiological conditions, the intima mainly comprises endothelial cells and a few monocyte/macrophages and dendritic cells; the media consists of smooth muscle cells and elastic fibers; and the adventitia ...
Mohanta SK, Hong M, Deng X, Dou X, Xu X, Monjezi M, Li Y, Sun T, Wang Z, Habenicht AJR, Yin C.   +10 more
europepmc   +2 more sources

High efficacy therapy to prevent the formation of meningeal tertiary lymphoid organs after CXCL13 index screening in early multiple sclerosis [PDF]

Frontiers in Neuroscience
Postmortem studies have shown the presence of subpial inflammation with tertiary lymphoid organs (TLO) in the meninges of patients with progressive multiple sclerosis, playing an important role in the pathophysiology of the disease.
Ana C. Londoño, Ana C. Londoño, Carlos A. Mora   +2 more
doaj   +2 more sources

Deletion of the Candida albicans TLO gene family results in alterations in membrane sterol composition and fluconazole tolerance. [PDF]

PLoS ONE
Development of resistance and tolerance to antifungal drugs in Candida albicans can compromise treatment of infections caused by this pathogenic yeast species. The uniquely expanded C.
James O'Connor-Moneley, Jessica Fletcher, Cody Bean, Josie Parker, Steven L Kelly, Gary P Moran, Derek J Sullivan   +6 more
doaj   +2 more sources

Transportation and logistics observatories: Guidelines for a conceptual model

Transportation Research Interdisciplinary Perspectives, 2022
A conceptual model should illustrate the most significant concepts of a given problem domain and demonstrate relevant aspects related to that domain. In this paper, a conceptual model for a Transportation and Logistics Observatory (TLO) is proposed along
Lilian Campos Soares, Edilson Ferneda, Hércules Antonio do Prado   +2 more
doaj   +1 more source

Utjecaj pH vrijednosti tla i dodatka kelatnog agensa na sadržaj kadmija u pojedinim biljkama [PDF]

Kemija u Industriji, 2016
U ovom je radu ispitivan utjecaj pH tla i dodatka kompleksirajućeg agensa na sadržaj kadmija u pojedinim biljkama. Tlo upotrijebljeno za ovaj eksperiment uzeto je s površina uz prometnicu u neposrednoj blizini Željezare u Zenici.
Farzet Bikić, Amira Pašalić
doaj   +1 more source

Development of Flow Type Cesium Removing Device Using Fluorinated Solvent [PDF]

MATEC Web of Conferences, 2021
In order to simultaneously achieve separation and volume reduction of radioactive cesium in the aqueous solution, we proposed a solvent extraction using a fluorinated solvent which is a nonflammable liquid having a low boiling point and is easy to ...
Suzuki Motoshi, Tajima Hideo, Kikuchi Aoi, Taguchi Youji, Nanba Shou-ichi   +4 more
doaj   +1 more source

A comparison of the 1-year surgical outcomes of ab externo trabeculotomy and microhook ab interno trabeculotomy using propensity score analysis

BMJ Open Ophthalmology, 2020
Objective To compare the 1-year outcomes of trabeculotomy ab externo (ab externo TLO) and trabeculotomy ab interno using a microhook (ab interno TLO) for glaucoma patients using propensity score analysis.Methods and analysis The medical charts of 65 ...
Sotaro Mori, Yusuke Murai, Kaori Ueda, Mari Sakamoto, Takuji Kurimoto, Yuko Yamada-Nakanishi, Makoto Nakamura   +6 more
doaj   +1 more source