The RNA Binding Protein TLS Is Translocated to Dendritic Spines by mGluR5 Activation and Regulates Spine Morphology [PDF]
Ritsuko Fujii +8 more
openalex +1 more source
NIBAN2/FLII/RREB1 Axis Drives Glioma Stem Cell Malignancy via TLR3 Pathway Activation
NIBAN2, highly expressed in glioma stem‐like cells (GSCs), assembles with FLII and transcription factor RREB1 to form a nuclear complex. This complex transcriptionally activates stemness‐associated genes (e.g., CD44, NANOG) and metabolic enzymes (e.g., LDHA), thereby sustaining both transcriptional and metabolic stemness programs.
Liang liang Shi +14 more
wiley +1 more source
Tertiary lymphoid structures in genitourinary cancers: a comprehensive review. [PDF]
Abreu A +7 more
europepmc +1 more source
Machine Learning Interpretability Meets TLS Fingerprinting [PDF]
Mahdi Jafari Siavoshani +4 more
openalex +1 more source
PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao +24 more
wiley +1 more source
Mature tertiary lymphoid structures tumor microenvironment-based risk model to assess patients with pancreatic ductal adenocarcinoma. [PDF]
Gu Z, He C, Cheng S, Su Q, Yu J.
europepmc +1 more source
A femtosecond UV pump–probe microscope resolves binding‐induced changes in protein excited‐state dynamics and converts these intrinsic contrasts into an equilibrium affinity readout. By probing tryptophan responses directly in solution, the approach enables quantitative determination of dissociation constants without labeling or immobilization ...
Jianghao Shen +5 more
wiley +1 more source
Initiation of Tertiary Lymphoid Structures for Cancer Immunotherapy. [PDF]
Zou JY, Li ZT, Wang ZC, Li H, Sun ZJ.
europepmc +1 more source
A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP. [PDF]
Hélène Zinszner +2 more
openalex +1 more source

