Results 171 to 180 of about 165,935 (290)

TDO2-Associated Tryptophan Metabolism Correlates with Impaired Tertiary Lymphoid Structure Maturation and Reduced B Cell Class Switching in Breast Cancer. [PDF]

Oncol Res
Yang W, Xiao W, Xu W, Ren L, Li X, Yu J, Wang R.   +6 more
europepmc   +1 more source

Determining the Minimal Clinically Important Difference of the 40‐Item Smell Identification Test in People With Cystic Fibrosis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and olfactory dysfunction (OD) are highly prevalent among people with cystic fibrosis (PwCF) and negatively impact quality of life. The 40‐item Smell Identification Test (SIT) is widely used to assess psychophysical olfaction, but a CF‐specific minimal clinically important difference (MCID) has not been ...
Eugene Oh, Jessa E. Miller, Michelle J. Lee, Anna Zemke, David Baraghoshi, Matthew J. Strand, Jeremiah A. Alt, Todd E. Bodner, Michael Chang, Naweed I. Chowdhury, Patricia H. Eshaghian, Anne E. Getz, Jennifer L. Goralski, David A. Gudis, Peter H. Hwang, Ashoke Khanwalkar, Adam J. Kimple, Jivianne T. Lee, Douglas A. Li, Jess C. Mace, Jayakar V. Nayak, Jonathan B. Overdevest, Zara Patel, Daniella K. Safatian, Rodney J. Schlosser, Brent Senior, Amanda L. Stapleton, Timothy L. Smith, Zachary M. Soler, Jeffrey D. Suh, Grant A. Turner, Marilene B. Wang, Milene T. Saavedra, Jennifer L. Taylor‐Cousar, Daniel M. Beswick   +34 more
wiley   +1 more source

The Age at Onset of LRRK2 p.Gly2019Ser Parkinson's Disease Across Ancestries and Countries of Origin

Annals of Neurology, EarlyView.
Objectives The objective of this study was to elucidate differences in the cumulative incidence of Leucine‐rich repeat kinase 2 (LRRK2) p.Gly2019Ser‐related Parkinson's disease (PD; LRRK2‐PD) between ancestries and countries. Methods We included 922 unrelated p.Gly2019Ser variant carriers (affected = 762 and unaffected = 160) from the Global Parkinson ...
Theresa Lüth, Björn‐Hergen Laabs, Sebastian Sendel, Inke R. König, Amke Caliebe, Alastair J. Noyce, Laurel A. Screven, Soraya Bardien, Matthew Farrer, Faycel Hentati, Rim Amouri, Christine Klein, Samia Ben Sassi, Joanne Trinh, Global Parkinson's Genetics Program (GP2)   +14 more
wiley   +1 more source

Tertiary lymphoid structures in the era of cancer therapy. [PDF]

J Exp Clin Cancer Res
Hernández-Verdin I, Dimberg A, Thommen DS, Engblom C, Vanhersecke L, Silina K, Bruno TC, Fridman WH, Nisticò P, Sautès-Fridman C.   +9 more
europepmc   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Association of CCL21⁺ CAFs with B-cell recruitment and TLS maturation in penile squamous cell carcinoma. [PDF]

Cancer Immunol Immunother
Li X, Chen D, Guo Y, Huang G, Cai Z, Xue T, Chen Z, Han H, Li Z.   +8 more
europepmc   +1 more source

Tertiary lymphoid structures guided opportunities and challenges for immunotherapy in early gastroesophageal junction cancer and low rectal cancer. [PDF]

Hum Vaccin Immunother
Zou Q, Zhang Y, Xian Z, Fang Z, Zhang J, Shang L, Wang H, Hu B, Chen Z.   +8 more
europepmc   +1 more source

Spatial and phenotypic plasticity of B cells in remodeling the tumor microenvironment. [PDF]

J Immunother Cancer
Gao Y, Peng Y, Chen Y, Zeng S, Shen H, Martin A, Cai C, Han Y.   +7 more
europepmc   +1 more source

TLS-grapevine2024: A terrestrial laser scanner point cloud dataset of grapevines at different phenological stages. [PDF]

Data Brief
Ferreira L, Marques P, Portela F, Sousa JJ, Peres E, Morais R, Pádua L.   +6 more
europepmc   +1 more source

Research on Evaporation Characteristics and Safe Storage Duration of Marine Liquid Hydrogen Storage Tanks Under the Coupling Effect of Heat Leakage and Sloshing

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Liquid hydrogen, a zero‐carbon and high–energy‐density fuel, is a promising option for future oceangoing vessels. During maritime transportation, onboard cryogenic tanks are exposed to ambient heat leakage and ship‐induced roll motion, which can trigger sloshing and fundamentally modify the coupled thermo‐fluid processes governing boil‐off and
Yan Deng, Wenfeng Wu, Zhenyu Zhao, Rongsheng Lin, Liangyi Sun, Youfei Liu   +5 more
wiley   +1 more source