Results 201 to 210 of about 58,438 (289)

Target-Specificity and repeatability in neuro-cardiac-guided TMS for heart-brain coupling. [PDF]

Transl Psychiatry
Feng ZJ, Martin S, Numssen O, Weise K, Jing Y, Gerardos G, Martin C, Hartwigsen G, Knösche TR.   +8 more
europepmc   +1 more source

NUP85 Mediates Endoplasmic Reticulum Stress through the USP47/ASK1 Signaling Pathway to Regulate the Progression of Liver Fibrosis

Advanced Science, EarlyView.
In the present study, we have demonstrated that the NUP85‐USP47‐ASK1 signaling pathway may have regulated the progression of liver fibrosis through modulating ERS. Additionally, we have developed a CREKA‐coupled liposome to target delivery of MV, a pharmacological inhibitor of NUP85, to activated HSCs, thereby attenuating liver fibrosis. ABSTRACT Liver
Dashuai Yang, Haoran Yang, Linxin Pan, Chang Tian, Fucheng Zuo, Shilei Huang, Xianrui Li, Ming Chen, Cheng Qian, Jie Wang, Zhaolin Chen, Tao Xu   +11 more
wiley   +1 more source

Recognizing EEG responses to active TMS vs. sham stimulations in different TMS-EEG datasets: A machine learning approach. [PDF]

Neuroimage
Keihani A, Donati FL, Russo S, Parmigiani S, Solbiati M, Casali AG, Fecchio M, Chaichian O, Rothwell J, Massimini M, Rocchi L, Rosanova M, Ferrarelli F.   +12 more
europepmc   +1 more source

NIPAL1 Drives a Metabolic‐Epigenetic Feedback Loop to Promote Lactate‐Mediated Immune Evasion in Esophageal Cancer

Advanced Science, EarlyView.
The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen, Xiao‐Dan Ma, Shui‐Dan Xu, Ao‐Tian Mo, Min‐Hua Deng, Jun‐Han Wu, Wei‐Tao Zhuang, Jin‐Ling Duan, Shu‐Huan Xie, Jin‐Long Lin, Peng Lin, Ji‐Ming Tang, Hai‐Yu Zhou, Xiao‐Song Ben, Gui‐Bin Qiao, Dan Xie   +15 more
wiley   +1 more source

Application of Electric-Field-Optimized Augmented Reality-Guided Neuronavigation in Transcranial Magnetic Stimulation. [PDF]

J Clin Med
Ritter P, Freigang S, Valentin A, Zaar K, Reishofer G, Jehna M, Michenthaler M, Karakaya S, Moser P, Frank L, Prückl R, Schaffelhofer S, Thumfart S, Fresnoza SM, Ischebeck A, Wolfsberger S, Mahdy Ali K.   +16 more
europepmc   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Progress in non-invasive neuromodulation based on consciousness-related neural circuits: a narrative review. [PDF]

Front Neurol
Wang Y, Zhai Y, Zheng Z, Wang N, Chai X, Niu H, Jia Y, Zhu S, Shang Y, Wan K, Cao T, He Q, Zhang T, Qiu H, Yang Y.   +14 more
europepmc   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Association Between Serum PADI-4 Levels and Disease Activity in Ulcerative Colitis Patients. [PDF]

Gastroenterol Res Pract
Şimşek S, Işık E, Yortanlı BÇ, Çekiç C.   +3 more
europepmc   +1 more source

3D Large‐Scale Subwavelength‐Resolution Sound Sheet Tomography Based on an Active and Programmable Circular Meta‐Array

Advanced Science, EarlyView.
A programmable 2048‐element circular ultrasound array combined with a compact acoustic lens produces a thin “sound sheet” over a large field of view, and records echoes with wide angular diversity across the ring aperture. Coherence‐enhanced beamforming converts full‐matrix data into high‐contrast tomographic slices, delivering near‐diffraction‐limited
Qiu‐De Zhang, Zi‐Bin Lin, Zhuo Chen, Zhao‐Hui Liu, Jin‐Lian He, Jun‐Jie Song, Long‐Sheng Zeng, Liang Zhou, Ming‐Yue Ding, Yu‐Gui Peng, Ming Yuchi, Xue‐Feng Zhu   +11 more
wiley   +1 more source