Results 111 to 120 of about 26,628 (256)

HIV-1 neutralizing activity of purified TNC in the presence of anti-HIV-1 antibodies.

, 2016
(A) IgG from breast milk of HIV-infected women inhibited TNC neutralization against HIV-1 C.DU156 whereas breast milk IgG from uninfected women did not. (B) The presence of either a control (CH65, anti-hemagglutinin) or anti-V3 antibody (CH22, 100 μg/ml)
Tomoo Ohashi (2373616), Harold Erickson (2793220), Sallie R. Permar (161600), Robin G Mansour (2793226), Frederick Jaeger (202894), Joshua Amos (2793223), S. Munir Alam (164023), Erin McGuire (2793211), Genevieve Fouda (2793217), Kimberly Barbas (2793208), Lisa Stamper (2793214)   +10 more
core   +1 more source

PDGFD‐Rearranged Dermatofibrosarcoma Protuberans With S100 and Pan‐TRK Expression

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Dermatofibrosarcoma protuberans (DFSP) is a fibroblastic malignancy characterized in most cases by COL1A1::PDGFB fusion. Rare cases exhibit alternative rearrangements involving PDGFD. Here, we describe a female patient in her third decade of life who presented with a spindle cell proliferation on the shoulder.
Venezia Podesta, May P. Chan, Douglas Rottmann, Kelly L. Harms, Paul W. Harms   +4 more
wiley   +1 more source

Tenascin-C drives cardiovascular dysfunction in a mouse model of diabetic cardiomyopathy

Cardiovascular Diabetology
Background Diabetic cardiomyopathy (DCM) is a complex condition linked to diabetes, characterized by cardiac and vascular dysfunction, frequently concomitant with heart failure with preserved ejection fraction.
Zsuzsanna Arnold, Christopher Dostal, Petra Lujza Szabó, Ibrahim Aykac, Ana Isabel Antunes Goncalves, Silva Laura Sousa, Simge Baydar, Heidi Budde, Barnabás Váradi, György L. Nadasy, Mária Szekeres, Camilla Hage, Lars H. Lund, Sarah Costantino, Dietmar Abraham, Karin Zins, Seth Hallström, Martin Bilban, Bence Ágg, Nazha Hamdani, Péter Ferdinandy, Francesco Paneni, Attila Kiss, Bruno K. Podesser   +23 more
doaj   +1 more source

Functional and transcriptomic analyses in Neurospora crassa reveal a crucial role for the N‐glycoprotein deglycosylation process in fungal homeostasis

The FEBS Journal, EarlyView.
In Neurospora crassa, a cytosolic GH18 endo‐β‐n‐acetylglucosaminidase (ENGase) functions as an active deglycosylating enzyme. Deletion of this severely alters tolerance to multiple stress conditions and causes extensive transcriptomic reprogramming, including upregulation of a GH20 exo‐β‐n‐acetylhexosaminidase under ER stress, indicating that N. crassa
Anastasios Samaras, Tanim Jabid Hossain, Magnus Karlsson, Georgios Tzelepis   +3 more
wiley   +1 more source

Tenascin C+ myofibroblasts exacerbate vascular neointimal hyperplasia by propagation of nerve-macrophage interactions in mice

Nature Communications
Neointimal hyperplasia (NIH) is a major pathological feature of vascular injury, yet its cellular and molecular drivers remain elusive. Here, using a mouse model of ligation-induced carotid artery NIH, we identify a population of Tenascin C-expressing ...
Xinran Tong, Guangzheng Shi, Zilong Fang, Sibei Tang, Bin Zhou, Qingyou Meng, Peili Zhang, Haixiang Li, Xiaojie Cai, Zhikai Wang, Xichen Zheng, Wendong Chen, Gonghao Jiang, Honglin Wang, Dongsheng Jiang, Qun Li   +15 more
doaj   +1 more source

Novel targets in headache: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra, Peter J. Goadsby, Carolina Oldoni, Stephen Silberstein, Fred Cohen, Simon Akerman   +5 more
wiley   +1 more source

Orofacial pain disorder or trigeminal autonomic cephalalgia? Insights into pathophysiology and implications in medicine and dentistry

Headache: The Journal of Head and Face Pain, EarlyView.
There are some headache disorders known as trigeminal autonomic cephalalgias (TACs). When these “headaches” are localized in the mid‐face region, they are known as “trigeminal autonomic orofacial pains” (TAOPs), and they can mimic other types of face pains including dental pain, which puts the patient at risk of receiving treatments that are incorrect.
Marcela Romero‐Reyes, Simon Akerman
wiley   +1 more source

Integrated chemical profiling, transcriptomics and functional validation elucidate the multifunctional benefits of a triple‐ferment filtrate complex for skin aging intervention

International Journal of Cosmetic Science, EarlyView.
Integrated chemical profiling, transcriptomics and functional validation reveal the multifunctional benefits of a triple‐ferment filtrate complex for skin aging intervention. Abstract Objective Skin aging is driven by interconnected hallmarks including oxidative stress and chronic low‐grade inflammation, cellular senescence, impaired epidermal function
Ping Gao, Xue Xiao, Hong Zhang, Fengjuan Tu, Xuelan Gu   +4 more
wiley   +1 more source

Globalizing retail: conceptualizing the distribution-based TNC

, 2005
In this article we argue that the retail transnational corporation (TNC) is an entity that merits urgent theoretical and empirical investigation from economic geographers. Using recent theoretical developments that conceptualize TNCs as the complex nexus
Coe, N.M., Wrigley, N., Wrigley, Neil, Currah, A.D., Coe, Neil M., Neil Wrigley, Neil M. Coe, Andrew Currah, Currah, Andrew   +8 more
core   +1 more source

Extracellular Matrix Remodeling in Actinic Cheilitis and Lip Squamous Cell Carcinoma: A Cross‐Sectional Study

Oral Diseases, EarlyView.
ABSTRACT Background Actinic cheilitis is a precursor to lip squamous cell carcinoma. How ultraviolet‐induced stromal degeneration relates to invasion‐related extracellular matrix markers remains unclear. This study investigated basophilic degeneration of collagen, solar elastosis, fibronectin, tenascin‐C, and podoplanin in both lesions.
Caroline Alfaia‐Silva, Polyane Caroline Arruda de Farias, Fernanda de Mello da Silva, Lidiane de Paula Ribeiro, Ericles de Paiva Vieira, Elena Riet Correa Rivero, Filipe Modolo   +6 more
wiley   +1 more source