Results 201 to 210 of about 3,516,666 (358)

TNF-α induces dedifferentiation of A7r5 cells by an autophagy-dependent pathway.

, 2018
(A) Western blot analysis of α-SMA and SM22 (n = 3–4; *ppB) collagen type I and osteopontin (n = 3–4; **pC) Visualization of actin filaments in A7r5 cells stained with rhodamine-phalloidin after treatment with TNF-α (100 ng/mL) for 48 h in the presence ...
Nicole Cancino-Arenas (5210993), Jaime A. Riquelme (2967201), Constanza Nuñez-Soto (5210996), Fernanda Sanhueza-Olivares (5211002), David Mondaca-Ruff (5211005), Alejandra San Martín (484118), Ignacio Norambuena-Soto (5211011), Marina García-Miguel (5210999), Pablo E. Morales (5211008), Mario Chiong (2179764)   +9 more
core   +1 more source

PMS13 EXPERIMENTAL STUDY OF TOPICAL TREATMENT OF RHEUMATOID ARTHRITIS WITH TNF-Α ANTAGONIST [PDF]

Value in Health, 2019
openaire   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

TNF-α Levels Are Increased in Patients with Subjective Cognitive Impairment and Are Negatively Correlated with β Amyloid-42

Antioxidants
The role of tumor necrosis factor-α (TNF-α) in Alzheimer’s disease (AD) has recently become a topic of debate. TNF-α levels increase in the blood of patients with AD, and amyloid beta (Aβ) plaques contain TNF-α deposits.
Sara Serafini, Gabriella Ferretti, Paola Monterosso, Antonella Angiolillo, Alfonso Di Costanzo, Carmela Matrone   +5 more
doaj   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

TNF-α induces a pro-inflammatory phenotypic shift in monocytes through ACSL1: relevance to metabolic inflammation

Background/aims: TNF-α-mediated pro-inflammatory phenotypic change in monocytes is known to be implicated in the pathogenesis of metabolic inflammation and insulin resistance. However, the mechanism by which TNF-α-induces inflammatory phenotypic shift in
Fahd Al-Mulla (18535589), Mina Amin Iskandar (10003022), Zunair Ahmad (19191538), Rasheed Ahmad (412118), Jaakko Tuomilehto (65635), Fatema Al-Rashed (9077046)   +5 more
core   +2 more sources

TNF-α is a significant inhibitor of Shh biological activity in vitro.

, 2017
The inhibitory effect of human recombinant TNF-α (hr TNF-α) is shown based on luminescence assay and linear regression plots are shown with corresponding p values.
Randy Peterson (3723376), Fan Jiang (144211), Xiaoxing Ma (325109), John Turnbull (342576), Anna Drannik (3723370), Joan Martin (3723373)   +5 more
core   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Electropolymerized Aptasensor for Femtogram‐Level Cytokine Detection

Advanced Materials, EarlyView.
Electropolymerization of 3‐amino‐ʟ‐tyrosine creates ultrathin, smooth, and chemically robust pALT nanofilms with accessible carboxyl functionalities for direct aptamer immobilization. Integrated with fiber‐optic SPR and OECT platforms, these interfaces enable IL‐6 detection down to 100 fg mL−1 and provide a versatile route to bioelectronic sensing ...
Jiyao Yu, Renan Colucci, Rachel X. Shi, Qi Lu, Tommaso Marchesi D'Alvise, Ulrike Kraft, Christopher V. Synatschke, Tanja Weil   +7 more
wiley   +1 more source

Pengaruh Pemberian Minyak Atsiri Daun Kemangi (Ocimum Basillicum) terhadap Kadar Tnf-Α pada Tikus Wistar yang diberi Aktivitas Fisik Berlebih

Seminar Ilmiah Nasional Teknologi, Sains, dan Sosial Humaniora (SINTESA)
Penuaan merupakan salah satu penyebab utama kerusakan struktur dan fungsi molekul seluler. Salah satu teori mekanistik yang mendasari penuaan adalah "teori radikal bebas", yang menyatakan bahwa penuaan dan penyakit terkait dipicu oleh kerusakan radikal bebas pada makromolekul seluler dan ketidakmampuan sistem antioksidan endogen untuk mengatasi ...
Ari Tirtayasa, Made Jawi, Adiartha Griadhi   +2 more
openaire   +1 more source