Results 41 to 50 of about 1,312,052 (154)
Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development [PDF]
Aspergillosis is a common fungal infection with systemic characteristics, which is caused by various species of Aspergillus. The infection could develop in immunocompromised and immunocompetent patients under specific circumstances. Based on the clinical
Ali AL-Janabi
doaj +1 more source
Use of each TNF inhibitor in patients with RA or AS since the approval of TNF inhibitors: Proportions of each TNF inhibitor used by patients with RA or AS since the approval of TNF inhibitors.
Seul Gi Im (4902652) +7 more
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Valentina Perrone,1 Serena Losi,2 Silvia Sabatino,2 Maurizio Mezzetti,3 Melania Dovizio,1 Diego Sangiorgi,1 Luca Degli Esposti1 1CliCon S.r.l., Società Benefit-Health Economics and Outcomes Research, Bologna, 40137, Italy; 2Eli Lilly Italy S.p.A, Sesto ...
Perrone V +6 more
doaj
Objective:Our aim was to compare the bone mineral density (BMD) levels in axial spondyloarthropathy (AxSpA) patients treated with tumor necrosis factor-α (TNFα) agents and interleukin-17 (IL-17) blockers.Materials and Methods:This retrospective study was
Nur Ferhatlar +4 more
doaj +1 more source
Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers [PDF]
Objectives: Our study sought to elucidate the role of oxidative stress for shedding of tumor necrosis factor-α (TNF-α) and for activating TNF-α-converting enzyme (TACE).
Welsch, Ulrich +4 more
core +1 more source
Inhibitors of tumor necrosis factor-a and mechanisms of their action [PDF]
Tumor necrosis factor (TNF)-a is a proinflammatory cytokine with a role in immunity to pathogens, as well as in the pathogenesis of several autoimmune/inflammatory diseases. Biological drugs targeting this cytokine and inhibiting its effects are designed.
Bufan Biljana +2 more
doaj +1 more source
Gingival and periodontal disorders associated with Tumor Necrosis Factor inhibitors (TNF inhibitors)
TNF inhibitors are widely used in inflammatory rheumatological diseases like Rheumatoid Arthritis (RA) or Ankylosing Spondylitis (AS). After the reporting in the Grenoble pharmacovigilance center of a case of gingivorrhagia in a patient treated with ...
Charles Khouri
core +1 more source
Inhibitor of Apoptosis Proteins as Novel Targets in Inflammatory Processes [PDF]
Objective: Inhibitor of apoptosis proteins (IAPs), such as X-linked or cellular IAP 1/2 (XIAP, cIAP1/2), are important regulators of apoptosis. IAP antagonists are currently under clinical investigation as anticancer agents.
Mayer, Bettina A. +10 more
core +1 more source
INTRODUCTION: The aim of our study is to determine, from data of the Moroccan register of biotherapies, the factors influencing the choice of the first prescribed biological treatment.
Meryem Eddaoudi +16 more
doaj +1 more source
Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF [PDF]
Tumour necrosis factor (TNF) is a trimeric protein which signals through two membrane receptors, TNFR1 and TNFR2. Previously, we identified small molecules that inhibit human TNF by stabilising a distorted trimer and reduce the number of receptors bound ...
Porter, John +21 more
core +1 more source

