Results 81 to 90 of about 1,312,052 (154)

Changes in expression of TNF alpha and its receptors mRNAs in oocytes and granulosa cells in mice with experimental immune ovarian failure [PDF]

, 2014
Purpose: To investigate the expression of TNF- α and its receptors (types I and II) at mRNA level in oocytes and granulose cells as well as to study effect of TNF-α on follicular cell death in mice with experimental immune ovarian failure induced by ...
Grushka, Nataliya, Dosenko, Victor, Shepel, Elena, Voznesenskaya, Tatyana, Yanchiy, Roman   +4 more
core   +1 more source

TNF-α levels and presence of SNP-308G/A of TNF-α gene in temporomandibular disorder patients

, 2022
Introduction: Temporomandibular disorder (TMD) refers to a group of conditions that compromise the harmonious movement and function of the temporomandibular joint, masticatory muscles, and associated structures.
Renata Silva Melo FERNANDES (12853596), Camilla Porto CAMPELLO (12833819), Elker Lene Santos de LIMA (12833822), Maria Tereza Cartaxo MUNIZ (12833828), Mirza PORTO (12853599)   +4 more
core   +1 more source

Structure-based discovery of natural-product-like tnf-α inhibitors

, 2010
(Figure Presented) Small but effective: Two natural-productlike inhibitors of tumor necrosis factor α (TNF-α represented in green in the picture) have been identified using structure-based virtual screening.
Chan, DSH, Lee, HM, Che, CM, Wong, CCL, Leung, CH, DikLung, M, Yang, F, Abagyan, R   +7 more
core   +1 more source

RMD commentary, JAK kinase inhibitors: a preferred alternative to TNF inhibitors?

RMD Open, 2021
Vibeke Strand
doaj   +1 more source

B-cell phenotype and IgD-CD27- memory B cells are affected by TNF-inhibitors and tocilizumab treatment in rheumatoid arthritis.

PLoS ONE, 2017
BackgroundThe use of TNF-inhibitors and/or the IL-6 receptor antagonist, tocilizumab, in rheumatoid arthritis (RA) have pleiotropic effects that also involve circulating B-cells.
Rita A Moura, Cláudia Quaresma, Ana R Vieira, Maria J Gonçalves, Joaquim Polido-Pereira, Vasco C Romão, Nádia Martins, Helena Canhão, João E Fonseca   +8 more
doaj   +1 more source

Use of leflunomide plus TNF-α inhibitors in rheumatoid arthritis

, 2013
Rheumatoid arthritis (RA) is a chronic inflammatory immune-mediated systemic disease which primarily affects the joints. Leflunomide (LFN) is a disease modifying anti-rheumatic drugs (DMARDs) which acts by inhibiting the synthesis of pyrimidines. Several
PUPPO, FRANCESCO, SPANO', FRANCESCA, MURDACA, GIUSEPPE   +2 more
core   +1 more source

Switch Rates and Total Cost of Care Associated with Apremilast and Biologic Therapies in Biologic-Naive Patients with Plaque Psoriasis

ClinicoEconomics and Outcomes Research, 2020
David L Kaplan,1 Brian L Ung,2 Corey Pelletier,2 Chuka Udeze,2 Ibrahim Khilfeh,3 Marc Tian2 1Adult & Pediatric Dermatology, Overland Park, Kansas, USA; 2US HEOR, Celgene Corporation, Summit, New Jersey, USA; 3US HEOR, Amgen Inc, Thousand Oaks ...
Kaplan DL, Ung BL, Pelletier C, Udeze C, Khilfeh I, Tian M   +5 more
doaj  

Inhibition of IgE-induced mast cell histamine release, cysLT generation and TNF synthesis by various inhibitors.

, 2013
Inhibition of IgE-induced mast cell histamine release, cysLT generation and TNF synthesis by various inhibitors.
Ewa Brzezińska-Błaszczyk (478075), Magdalena Wiktorska (478074), Aleksandra Słodka (478073)   +2 more
core   +1 more source

TNF Inhibitors in Dermatology: From Thalidomide to Biologics

, 2010
Inflammatory skin diseases represent an important part of dermatological pathology. Recent advances in the understanding of inflammatory processes have identified various cytokines, and in particular Tumor necrosis factor (TNF) as a potent and central ...
Laffitte, Emmanuel Alexis
core   +1 more source

HLA alleles, TNFA and TNFRSF1A genetics and response to TNF-α inhibitors.

, 2018
HLA alleles, TNFA and TNFRSF1A genetics and response to TNF-α inhibitors.
Stefania Moz (287034), Carlo-Federico Zambon (287048), Ada Aita (730561), Roberta Ramonda (3448175), Filippo Navaglia (287050), Andrea Padoan (287039), Mario Plebani (287058), Daniela Basso (287016), Mariagrazia Lorenzin (5007605), Leonardo Punzi (444289)   +9 more
core   +1 more source