Results 71 to 80 of about 614,943 (309)

Genome-wide identification and characterization of ABA receptor PYL/RCAR gene family reveals evolution and roles in drought stress in Nicotiana tabacum

open access: yesBMC Genomics, 2019
Background Abscisic acid (ABA) is an important phytohormone for plant growth, development and responding to stresses such as drought, salinity, and pathogen infection.
Ge Bai   +9 more
doaj   +1 more source

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao   +14 more
wiley   +1 more source

Should the health community promote smokeless tobacco (snus): comments from British American Tobacco. [PDF]

open access: yesPLoS Medicine, 2007
Justine Williamson   +2 more
doaj   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen   +18 more
wiley   +1 more source

NLSS3 Impairs SHM1 Autophagic Degradation to Regulate Leaf Morphology and Salt Tolerance in Rice

open access: yesAdvanced Science, EarlyView.
In rice, NLSS3 binds and shields SHM1 from autophagic degradation to maintain serine homeostasis. The A132P mutation in nlss3 disrupts this, triggering SHM1 loss, metabolic dysfunction, K+ imbalance, and impaired ROS scavenging, which collectively drive narrow leaves and salt sensitivity.
Xiong Liu   +15 more
wiley   +1 more source

21.02.002: "Mayo’s Tobacco, Always Good" with image of Rooster [PDF]

open access: yes
Mayo’s Tobacco, Always Good with image of Rooster; 3 x 2 cm [19-
Mayo Tobacco
core  

Bamboo as an alternative crop to smallholder tobacco farmers in South Nyanza region, Kenya [PDF]

open access: yes, 2010
Using photographs, the poster contrasts the benefits of bamboo production with the harmful intense farming practices necessary for tobacco ...
Tobacco To Bamboo
core  

Genome-wide characterization of ADF proteins in Nicotiana tabacum uncovers the critical role of NtADF22 in defense against black shank disease

open access: yesChemical and Biological Technologies in Agriculture
Background Tobacco is a vital economic crop, and its cultivation is severely threatened by black shank disease, caused by Phytophthora nicotianae (P. nicotianae).
Mengxiao Xu   +8 more
doaj   +1 more source

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

open access: yesAdvanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li   +10 more
wiley   +1 more source

Situational analysis of tobacco control in Kenya : report of the baseline assessment carried out by the Kenya Tobacco Control Situational Analysis Consortium [PDF]

open access: yes, 2008
The assessment describes the current status of tobacco control efforts in Kenya, what information is readily available in terms of published literature, the infrastructure already existing for tobacco control, and a SWOT analysis (Strengths, Weaknesses ...
Kenya Tobacco Control Situational Analysis Consortium
core   +1 more source

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