Results 221 to 230 of about 2,189,319 (256)

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima   +4 more
wiley   +1 more source

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto   +7 more
wiley   +1 more source

In Utero Alcohol and Tobacco Exposure, Maternal Depression, And Maternal Obesity Are Associated with Impaired Oligodendrocyte Differentiation in The Developing Brain. [PDF]

open access: yesObstet Gynecol Res
Bharai U   +11 more
europepmc   +1 more source

The Positive and Adverse Childhood Experiences (PACE) Framework for Counseling Youths

open access: yesJournal of Counseling &Development, EarlyView.
ABSTRACT Youth mental and behavioral health are significantly shaped by both adverse childhood experiences (ACEs) and positive childhood experiences (PCEs). Yet, counseling scholarship and training often address these domains separately, limiting their translation to counseling practice.
Isak Kim, Jaeyoung Kim, Gahyun Park
wiley   +1 more source

Discrete components of stress impact trajectories of childhood irritability but not adolescent mental health outcomes

open access: yesJCPP Advances, EarlyView.
Thick red line indicates positive mixture effect of stressors predicting high irritability class. Maternal demoralization, material hardship, maternal perceived stress, and intimate partner violence contributed to the mixture effect (thick borders on boxes).
Mariah DeSerisy   +8 more
wiley   +1 more source

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