Results 61 to 70 of about 2,189,319 (256)

Passive smoking is associated with poor asthma control during pregnancy: a prospective study of 500 pregnancies. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND AND AIM: Asthma and tobacco exposure is common among pregnant women. We investigated the effect of passive and active smoking on asthma control during pregnancy. METHODS: Prospective observational design.
Pernille A Grarup   +2 more
doaj   +1 more source

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

open access: yesAdvanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang   +17 more
wiley   +1 more source

Medicine students and exposure to environmental tobacco smoke [PDF]

open access: yes, 2013
Objective: Although medicine students express positive attitudes toward providing lifestyle counseling, they require more instruction in many areas of health behavior in order to be helpful to their patients.
Szumska, Magdalena   +9 more
core   +2 more sources

Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module

open access: yesAdvanced Science, EarlyView.
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang   +6 more
wiley   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

open access: yesAdvanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu   +12 more
wiley   +1 more source

Global burden and cross-national inequalities of tobacco-attributable cancers in adults aged 40 and above, 1990–2021: a population-based study

open access: yesFrontiers in Oncology
BackgroundTobacco exposure substantially increases the global cancer burden; however, studies targeting specific subgroups are scarce. We aimed to investigate global burden trends of tobacco-attributable cancers among people aged ≥40 and the associated ...
Yi Li   +4 more
doaj   +1 more source

Serum cotinine by socioeconomic status and exposure to second hand smoke in a national sample of South Africans

open access: yesTobacco Induced Diseases, 2018
Background Cotinine is a widely-used biomarker of exposure to tobacco for both active and second-hand smoke (SHS). Given South Africa's tobacco control laws restricting smoking in public places in the last decade, we assessed the prevalence and extent ...
Ronel Sewpaul   +2 more
doaj   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

open access: yesAdvanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan   +5 more
wiley   +1 more source

The effect of a smoking ban on exposure and cardio-respiratory health of non-smoking hospitality workers in Switzerland [PDF]

open access: yes, 2014
Summary: Background The first scientific studies on negative health effects of passive smoking published in the 1980s instigated an intense battle between the tobacco industry, who fear the loss of social acceptance of smoking and resultant financial ...
Rajkumar, Sarah Priya
core   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

open access: yesAdvanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang   +19 more
wiley   +1 more source

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