Harnessing Viral Proteases for Cellular and Molecular Engineering
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui+2 more
wiley +1 more source
Potential Implications for Tobacco Industry Transformation of the Acquisition of Swedish Match by Philip Morris International. [PDF]
Levy DT+6 more
europepmc +1 more source
Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano+8 more
wiley +1 more source
Tobacco industry pricing strategies for single cigarettes and multistick packs after excise tax increases in Colombia. [PDF]
Sheikh ZD+5 more
europepmc +1 more source
Canadian universities' links to tobacco industry shown [PDF]
David Spurgeon
openalex +1 more source
Farming Exit Decision by Age Group: Analysis of Tobacco Buyout Impact in Kentucky [PDF]
This article analyzes factors that affected the decision to exit tobacco production in the wake of the tobacco buyout program using the data collected through a survey of Kentucky tobacco farmers.
Pushkarskaya, Helen N.+1 more
core +1 more source
Lysergic acid diethylamide (LSD) is currently being investigated as a potential treatment for psychiatric and neurological disorders. Different LSD formulations (base or tartrate, oral or intravenous) are being used. Unclear is whether LSD base and tartrate pharmacokinetics are equivalent.
Denis Arikci+7 more
wiley +1 more source
Association between tobacco industry advertising expenses and tobacco advertising exposure among Korean adolescents. [PDF]
Nam HK, Kim H, Chun HR, Kang H.
europepmc +1 more source
Tobacco industry success in preventing regulation of secondhand smoke in Latin America: the “Latin Project” [PDF]
Joaquín Barnoya, S A Glantz
openalex +1 more source
Uncovering ESG Ratings: The (Im)Balance of Aspirational and Performance Features
ABSTRACT Environmental, Social, and Governance (ESG) scores are crucial for evaluating corporate sustainability. However, the undisclosed and complex methodologies used by rating agencies have raised concerns about their reliability and consistency. This study replicates LSEG's ESG scoring methodology using machine learning to shed light on the key ...
Andrea Ferro+2 more
wiley +1 more source