Results 81 to 90 of about 6,457,654 (397)

Divergent Regulatory Effects of Jasmonic Acid on Tomato Lycopene Biosynthesis Under Light and Dark Conditions

Advanced Science, EarlyView.
This study reveals the mechanism by which jasmonic acid (JA) regulates lycopene synthesis under light and dark conditions. In light, JA activates SlMYC2, which suppresses SlPIF1a and promotes SlPSY1 expression. In darkness, JA induces the acetyltransferase SlNATA1, which acetylates the dark‐accumulated SlPIF1a, thereby repressing SlPSY1 expression ...
Jiayi Xu, Lingfeng He, Jialong Zhang, Hao Cui, Hongxin Li, Haijun Zhang, Jiaojiao Zhang, Lun Liu, Kunpeng Xu, Yang‐Dong Guo, Na Zhang   +10 more
wiley   +1 more source

High-throughput Bronchus-on-a-Chip system for modeling the human bronchus

Scientific Reports
Airway inflammation, a protective response in the human body, can disrupt normal organ function when chronic, as seen in chronic obstructive pulmonary disease (COPD) and asthma.
Akina Mori, Marjolein Vermeer, Lenie J. van den Broek, Jeroen Heijmans, Arnaud Nicolas, Josse Bouwhuis, Todd Burton, Kazushi Matsumura, Kazuhiro Ohashi, Shigeaki Ito, Bart Kramer   +10 more
doaj   +1 more source

“Why Wouldn’t I Use It?”: Purdue Pharmaceutical’s Push of Pills [PDF]

, 2020
Throughout the early 1940’s to mid 1960’s, the popular habit of smoking cigarettes was not only condoned, but advertised by doctors and lawmakers. With the support of medical professionals and non-restrictive advertisement laws, the widespread use of ...
Fletcher, Gillian
core   +1 more source

Ethical blindness, EGMs and public policy : a tentative essay comparing the EGM and tobacco industries [PDF]

, 2007
Arguing a case by way of analogy can be perilous. Each problem has its own particulars that analogy and examples from other domains often obscure. Therefore it is with some trepidation that this paper discusses similarities and differences between the ...
Doughney, James
core   +1 more source

Digital media use and subsequent cannabis and tobacco product use initiation among adolescents.

Drug and Alcohol Dependence, 2020
BACKGROUND Digital media engagement, such as browsing the internet or social media posting, may be associated with cannabis and tobacco product use initiation among adolescents.
A. Kelleghan, A. Leventhal, T. Cruz, Mariel S. Bello, Fei Liu, J. Unger, K. Riehm, Junhan Cho, M. Kirkpatrick, R. McConnell, J. Barrington-Trimis   +10 more
semanticscholar   +1 more source

BLADE‐ON‐PETIOLE Genes Enable Genetic Bottleneck Mitigation Through Cross‐Species Repurposing of Floral Persistence Traits

Advanced Science, EarlyView.
This study shows that BLADE‐ON‐PETIOLE (BOP) proteins regulate floral abscission and senescence in tomato by interacting with TFAM1 to form transcriptional condensates controlling the ARABIDOPSIS THALIANA HOMEOBOX GENE 1 (ATH1)‐mediated abscission pathway.
Nan Xiao, Qianwen Lyu, Tinghao Zhang, Yupan Zou, Yue Xie, Dandan Yang, Cao Xu, Xiaozhen Huang   +7 more
wiley   +1 more source

KCNJ2 is Required for NLRP3 Inflammasome Activation That Drives Allergic Airway Inflammation and Remodeling

Advanced Science, EarlyView.
This study aims to evaluate the impact of the potassium channel KCNJ2 on asthma development. KCNJ2 promotes NLRP3 inflammasome activation through both Ca2+ influx and K+ efflux in airway epithelial cells, which drives allergic airway inflammation and remodeling, suggesting a promising therapeutic target for asthma.
Yachao Cui, Shumei Wu, Yang Peng, Yiqi Liu, Li Che, Shiying Chen, Feng Zhang, Dajiang Qin, Shiyue Li, Pixin Ran, Wenguang Yin   +10 more
wiley   +1 more source

Regulation and promotion of an addictive product : Spanish tobacco business in the spread of cigarette consumption (1880s to 1930s) [PDF]

, 2003
Tobacco is an addictive product, a big business and an important source of fiscal revenues. From 1880s to 1930s tobacco consumption spread in Western World mainly in the form of cigarettes.
Gálvez Muñoz, Lina
core   +2 more sources

Tobacco product use and susceptibility to use among sexual minority and heterosexual adolescents.

Preventive Medicine, 2020
Sexual identity is associated with tobacco use in adults. We examined tobacco use and susceptibility to use by sexual identity in adolescents. Data were collected in February 2019 via Qualtrics research participant panels. Data analyses were performed in
Luis C Garcia, Erin A. Vogel, J. Prochaska   +2 more
semanticscholar   +1 more source

The Maize ZmbHLH118 Transcription Factor Regulates Vacuolar Nitrate Loading by the NO3− Transporter ZmCLCa

Advanced Science, EarlyView.
In maize, the bHLH transcription factor ZmbHLH118 directly binds to the promoter of ZmCLCa and inhibits its expression. Tonoplast‐localized ZmCLCa mediates NO3− influx into the vacuole to regulate intracellular NO3− homeostasis, modulating nitrate uptake and metabolism, plant growth, and grain yield.
Chaonan Zhang, Elsa Demes‐Causse, Xujian Li, Zhenhui Guo, Hanshu Zhao, Huairong Cao, Yajing Song, Lijun Mu, Kaikai Zhang, Jing Zhang, Zhongtao Jia, Lixing Yuan, Alexis De Angeli, Jingbo Zhang   +13 more
wiley   +1 more source