Cancer Nexus, EarlyView.ABSTRACT Objective To compare the presence and quantification of selected periodontopathogenic bacterial species and salivary parameters between patients with head and neck cancer (HNC) treated with radiotherapy and patients with chronic periodontitis, using chronic periodontitis as a reference model of oral dysbiosis.
Tanya Pereira‐Riveros +4 more
wiley +1 more source
Beyond Combustion: Oxidative Stress as a Shared Pathway of Harm Across Conventional Cigarettes, Heated Tobacco Products, E-Cigarettes, and Waterpipe Smoking. [PDF]
Antioxidants (Basel)Loffredo L.
europepmc +1 more source
Intelligent Automation Improved Efficiency in Pharmacovigilance Safety Signal Assessment
Clinical Pharmacology &Therapeutics, EarlyView.Pharmacovigilance is the science involving the detection, assessment, understanding, and prevention of adverse events associated with drugs, biologics, or medical devices. In pharmacovigilance, information that suggests a new potential causal relationship between an intervention and an adverse event is called a safety signal. Following their detection,
Jeffrey Warner +3 more
wiley +1 more source
Smoking Status, Including Non-Combustible Nicotine or Tobacco Products Use, and Site-Specific Colorectal Cancer Risk: A Nationwide Cohort Study. [PDF]
Cancers (Basel)Kim S, Kim TS, Shin DW, Han K, Min BH.
europepmc +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke +12 more
wiley +1 more source
Representativeness of reach and effectiveness of proactive tobacco quitline follow<b>-</b>up treatment for adults who smoke tobacco products: Secondary analyses of a factorial experiment. [PDF]
Tob Prev CessatMcCarthy DE +9 more
europepmc +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho +12 more
wiley +1 more source
Correction: Assessing the Health Impacts of Heated Tobacco Products Compared to Traditional Tobacco Use: A Systematic Review of Current Evidence. [PDF]
CureusAmbildhok KA, Asawa K, Garcha V.
europepmc +1 more source
Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta
Clinical Pharmacology &Therapeutics, EarlyView.Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung +12 more
wiley +1 more source
The Effects of Heated Tobacco Products on Oral Health and Quality of Life: An Observational Cross-Sectional Study. [PDF]
Healthcare (Basel)Glavina A +6 more
europepmc +1 more source