Results 111 to 120 of about 339,667 (356)

Sustainability in Analytical Chemistry Illustrated by Pharmaceutical Nitrosamine Testing

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT Following the valsartan scandal in 2018, the testing of drug substances and drug products for N‐nitrosamines has become a critical and mandatory quality control measure. The European Pharmacopoeia chapter 2.5.42 currently describes three analytical methods for this purpose: HPLC–MS/MS, GC–MS, and GC–MS/MS.
Felix Bredendiek   +2 more
wiley   +1 more source

Influence of tobacco smoke on the pharmacokinetics of citalopram and its enantiomers [PDF]

open access: yes, 2012
The purpose of this study was to evaluate the influence of tobacco smoke on the pharmacokinetics of citalopram (CIT) and desmethylcitalopram (DCIT) and its enantiomers on an animal model.
Florek, Ewa   +5 more
core  

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Relationships between Serum Biomarkers of Oxidative Stress and Tobacco Smoke Exposure in Patients with Mental Disorders [PDF]

open access: gold, 2023
Ana-Maria Vlasceanu   +4 more
openalex   +1 more source

Patterns of Cervical Metastases and Implications for Neck Management in Minor Salivary Gland Cancer Treatment

open access: yesHead &Neck, EarlyView.
ABSTRACT Objectives Minor salivary gland cancer (MiSGC) is a rare and heterogeneous disease, with different degrees of tumor aggressiveness. The scarce data in the literature show that the presence of lymph node metastases (LNMs) negatively impacts the prognosis.
Eduardo Wanderley Estanislau da Costa   +6 more
wiley   +1 more source

Gas chromatography of volatile organic compounds [PDF]

open access: yes, 1973
System has been used for problems such as analysis of volatile metabolities in human blood and urine, analysis of air pollutants, and in tobacco smoke chemistry.
Zlatkis, A.
core   +1 more source

Dental Rehabilitation After Bone Mandibular Reconstruction for Head and Neck Cancer: A GETTEC Multicenter Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The microvascular bone free flap (MBFF) is the preferred reconstruction after mandibular resection as it facilitates secondary dental rehabilitation. Methods In this multicenter study, patients were included if treated between January 2017 and January 2022 for head and neck cancer with MBFF reconstruction.
Roussel Lise‐Marie   +11 more
wiley   +1 more source

Tobacco Smoke Exposure Exacerbated Crystalline Silica-Induced Lung Toxicity in Rats

open access: green, 2020
Tina M. Sager   +7 more
openalex   +2 more sources

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