Results 221 to 230 of about 333,227 (308)

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, EarlyView.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

Interactive Effects of Genetic Susceptibility and Early-Life Tobacco Smoke Exposure on the Asthma-Eczema Complex Phenotype in Children: 6-Year Follow-Up Case-Control Study. [PDF]

Int J Mol Sci
Dębińska A, Danielewicz H, Drabik-Chamerska A, Sozańska B.   +3 more
europepmc   +1 more source

Minimally invasive sacroiliac joint fusion: Primary endpoint results from the prospective, multicenter STACI study

PM&R, EarlyView.
Abstract Background Chronic sacroiliac joint (SIJ) pain is highly debilitating. Minimally invasive SIJ fusion has become a commonly performed surgical treatment for SIJ pain, with level I evidence showing clinically significant improvements in pain, function, and quality of life and a low adverse event rate.
Jacqueline Weisbein, Timothy Davis, Douglas Beall, Jack Smith, Caroline Harstroem, Daniel Kloster, Morteza Rabii, Robyn Capobianco, Ramana Naidu, Michael Harned, Christopher Mallard, the STACI investigators   +11 more
wiley   +1 more source

Joint association between tobacco smoke exposure and periodontitis and glycemic status. [PDF]

Front Endocrinol (Lausanne)
Hua X, Li J, Hu R, Zhang X.
europepmc   +1 more source

Investigating zeta‐cypermethrin resistance stability in California Drosophila suzukii populations

Pest Management Science, EarlyView.
After continuous selection and removal of selection pressure in spotted‐wing Drosophila, zeta‐cypermethrin resistance remained stable over several generations. Following a population bottleneck, zeta‐cypermethrin resistance increased without selection, highlighting the importance of insecticide rotation.
Nicolas Buck, Fatemeh Ganjisaffar, Frank G. Zalom   +2 more
wiley   +1 more source

The complexity of tobacco smoke-induced mutagenesis in head and neck cancer. [PDF]

Nat Genet
Torrens L, Moody S, de Carvalho AC, Kazachkova M, Abedi-Ardekani B, Cheema S, Senkin S, Cattiaux T, Cortez Cardoso Penha R, Atkins JR, Gaborieau V, Chopard P, Carreira C, Abbasi A, Bergstrom EN, Vangara R, Wang J, Fitzgerald S, Latimer C, Diaz-Gay M, Jones D, Teague J, Ribeiro Pinto F, Kowalski LP, Polesel J, Giudici F, de Oliveira JC, Lagiou P, Lagiou A, Vilensky M, Mates D, Mates IN, Arantes LM, Reis R, Podesta JRV, von Zeidler SV, Holcatova I, Curado MP, Canova C, Fabianova E, Rodríguez-Urrego PA, Humphreys L, Alexandrov LB, Brennan P, Stratton MR, Perdomo S.   +45 more
europepmc   +1 more source

Characterising Patient Pathways Prior to the Diagnosis of Interstitial Lung Disease

Respirology, EarlyView.
ABSTRACT Background and Objective Interstitial lung diseases (ILDs) lead to breathlessness, cough, deteriorating quality of life and early death. Patients are typically diagnosed late in their disease course when existing lung damage cannot be reversed.
Caitlin C. Fermoyle, John Townend, Vidya Navaratnam, Nicole Goh, Francesca Gonnelli, Neva Eleangovan, Ursie Smith, Heath Heatley, Victoria Carter, David B. Price, Richard Hubbard, Tamera J. Corte   +11 more
wiley   +1 more source

Naphthalene Metabolites From Long-Term Environmental Tobacco Smoke Induce the Aging of Retinal Pigment Epithelium. [PDF]

Aging Cell
Cui T, Ou Q, Wang Z, Zhou Y, Xu J, Liu Y, Bi Y, Jin X, Chen J, Gao F, Wang J, Zhang J, Lu L, Xu GT, Jin C, Tian H, Xu JY.   +16 more
europepmc   +1 more source

Iowa Population Exposures to Metals and Metalloids in Well Water

Environmental Toxicology, EarlyView.
ABSTRACT Previous Iowa studies suggest low levels and chronic arsenic exposures are associated with prostate cancer. The rural Iowa population heavily relies on private wells for drinking water resources and thus is vulnerable to contaminants such as heavy metals found in well water.
Donald L. Simmons, Brian Wels, Alyssa Mattson, Elizabeth M. Miller, Zachary E. Hoggarth, Maya Sternberg, Susie Y. Dai, Dustin May, Michael Schueller, Michael Pentella   +9 more
wiley   +1 more source

Targeted Analysis of Placental Steroid Hormones in Relation to Maternal Tobacco Smoke Exposure: Early Markers Relevant to DOHaD (Developmental Origins of Health and Disease). [PDF]

Int J Mol Sci
Kotłowska A, Fitzek S, Stettner R, Narkowicz S, Kiełbratowska B, Szefer P.   +5 more
europepmc   +1 more source