PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory +13 more
wiley +1 more source
Health effects of home energy efficiency interventions in England: a modelling study [PDF]
Objective: To assess potential public health impacts of changes to indoor air quality and temperature due to energy efficiency retrofits in English dwellings to meet 2030 carbon reduction targets. Design: Health impact modelling study.
Chalabi, Z +7 more
core +2 more sources
Glutathione peroxidase inhibitory assay for electrophilic pollutants in diesel exhaust and tobacco smoke [PDF]
We developed a rapid kinetic bioassay demonstrating the inhibition of glutathione peroxidase 1 (GPx-1) by organic electrophilic pollutants, such as acrolein, crotonaldehyde, and p-benzoquinone, that are frequently found as components of tobacco smoke, diesel exhaust, and other combustion sources.
Norbert, Staimer +3 more
openaire +2 more sources
ABSTRACT The present study seeks to advance the understanding of the determinants of occupational injuries, thereby enhancing both academic knowledge and decision‐making in the management and implementation of occupational health and safety measures.
Rosa María Cañaveras Perea +2 more
wiley +1 more source
Background Although many indoor public places have implemented smoke-free regulations, private homes have remained sources of tobacco smoke pollutants.
Jeonghoon Kim +5 more
doaj +1 more source
Malignant Transformation of Oral Epithelial Dysplasia in Southern Finland
ABSTRACT Background Oral epithelial dysplasia (OED) often precedes oral squamous cell carcinoma (OSCC). The aim was to elucidate the risk and time of malignant transformation (MT) of OED. Methods Patients diagnosed with OED between 2001 and 2011 in Helsinki and Uusimaa, Finland were included.
Katariina Leino +3 more
wiley +1 more source
This paper investigates the impacts of smoke-free housing policies on compliance, enforcement and smoking behavior. From 2012 to 2014, we studied two affordable housing providers in Canada with comprehensive smoke-free policies: Waterloo Regional Housing
Pamela Kaufman +4 more
doaj +1 more source
Particulate matter (PM) 2.5 levels in ETS emissions of a Marlboro Red cigarette in comparison to the 3R4F reference cigarette under open- and closed-door condition [PDF]
Introduction: Potential health damage by environmental emission of tobacco smoke (environmental tobacco smoke, ETS) has been demonstrated convincingly in numerous studies.
Ackermann, Hanns +5 more
core
Feasibility of Measuring Tobacco Smoke Air Pollution in Homes: Report from a Pilot Study. [PDF]
Tobacco smoke air pollution (TSAP) measurement may persuade parents to adopt smoke-free homes and thereby reduce harm to children from tobacco smoke in the home.
Brown, Nili +5 more
core +2 more sources
Ambient Particulate Air Pollution, Environmental Tobacco Smoking, and Childhood Asthma: Interactions and Biological Mechanisms [PDF]
The World Health Organization (WHO) estimates that 24% of the global burden of disease is caused by environmental factors that can be averted (1). Understanding the role of the environment in asthma is a natural ambition in the overall search to understand environmental burdens: In an individual expressing the asthmatic phenotype, worsening of asthma ...
A. Baccarelli, J. D. Kaufman
openaire +2 more sources

