Results 21 to 30 of about 362,387 (260)

Effects of moisture-preserving yellowing process optimization on cell physiology and post-curing chemical composition

open access: yesBMC Plant Biology
Background Yellowing is a critical post-harvest process that determines the flavor, quality, and economic value of crops, particularly tobacco (Nicotiana tabacum L.).
Ying Huang   +10 more
doaj   +1 more source

Support for tobacco endgame approaches: Results from a web-based survey of stakeholders from 28 African countries

open access: yesTobacco Induced Diseases
Introduction The tobacco ‘endgame’ concept proposes moving beyond traditional tobacco control measures towards a tobacco-free future. The aim of this study is to investigate the perceptions of tobacco control stakeholders in Africa on their agreement ...
Catherine O. Egbe   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Exploring hypermasculinity as a moderator between sexual violence victimization and adverse mental health effects among sentenced incarcerated men [PDF]

open access: yesJournal of Men's Health
Sexual assault is a common occurrence among incarcerated men in correctional facilities, and severely impacts the psychological well-being of the victim.
Sebenzile Nkosi   +3 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Associations between childbirth, gang exposure and substance use among young women in Cape Town, South Africa

open access: yesSubstance Abuse Treatment, Prevention, and Policy
The prevalence and influence of gangs on adolescents and young adults remain a concern in Western Cape, South Africa—particularly as they have one of the largest gang presence.
Felicia A. Browne   +4 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Disparities in Tobacco Smoking by Sex and Employment Status: Results from South Africa’s First Global Adult Tobacco Survey

open access: yesSocial Sciences
Background/Objectives: Tobacco smoking is a cause of premature death and illness globally. This study examined the prevalence and factors associated with tobacco smoking among South African adults according to sex, education, and employment status among ...
Catherine O. Egbe   +2 more
doaj   +1 more source

Biochemical Verification of Tobacco-Use as an Inclusion Criterion in Smoking Cessation Trials- Lessons From the Cessation of Smoking Trial in the Emergency Department

open access: yesTobacco Use Insights, 2023
INTRODUCTION Biochemical verification of smoking status prior to recruitment into smoking cessation trials is widely used to confirm smoking status, most commonly using exhaled carbon monoxide (CO).
Ian Pope MBBS   +4 more
doaj   +1 more source

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