Results 31 to 40 of about 363,052 (263)

Support for tobacco endgame approaches: Results from a web-based survey of stakeholders from 28 African countries

Tobacco Induced Diseases
Introduction The tobacco ‘endgame’ concept proposes moving beyond traditional tobacco control measures towards a tobacco-free future. The aim of this study is to investigate the perceptions of tobacco control stakeholders in Africa on their agreement ...
Catherine O. Egbe, Mukhethwa Londani, Siphesihle Gwambe, Leonce Sessou, Omotayo Francis Fagbule, Stella Bialous   +5 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Exploring hypermasculinity as a moderator between sexual violence victimization and adverse mental health effects among sentenced incarcerated men [PDF]

Journal of Men's Health
Sexual assault is a common occurrence among incarcerated men in correctional facilities, and severely impacts the psychological well-being of the victim.
Sebenzile Nkosi, Kopano Ratele, Yandisa Sikweyiya, Neo Morojele   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Associations between childbirth, gang exposure and substance use among young women in Cape Town, South Africa

Substance Abuse Treatment, Prevention, and Policy
The prevalence and influence of gangs on adolescents and young adults remain a concern in Western Cape, South Africa—particularly as they have one of the largest gang presence.
Felicia A. Browne, Tara Carney, Bronwyn Myers, Courtney Peasant Bonner, Wendee M. Wechsberg   +4 more
doaj   +1 more source

Biochemical Verification of Tobacco-Use as an Inclusion Criterion in Smoking Cessation Trials- Lessons From the Cessation of Smoking Trial in the Emergency Department

Tobacco Use Insights, 2023
INTRODUCTION Biochemical verification of smoking status prior to recruitment into smoking cessation trials is widely used to confirm smoking status, most commonly using exhaled carbon monoxide (CO).
Ian Pope MBBS, Chandhini Suresh MPH, Emma Ward PhD, Pippa Belderson PhD, Caitlin Notley PhD   +4 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Disparities in Tobacco Smoking by Sex and Employment Status: Results from South Africa’s First Global Adult Tobacco Survey

Social Sciences
Background/Objectives: Tobacco smoking is a cause of premature death and illness globally. This study examined the prevalence and factors associated with tobacco smoking among South African adults according to sex, education, and employment status among ...
Catherine O. Egbe, Portia Nevhungoni, Mukhethwa Londani   +2 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Study protocol for a pragmatic trial of the Consult for Addiction Treatment and Care in Hospitals (CATCH) model for engaging patients in opioid use disorder treatment

Addiction Science & Clinical Practice, 2019
Background Treatment for opioid use disorder (OUD) is highly effective, yet it remains dramatically underutilized. Individuals with OUD have disproportionately high rates of hospitalization and low rates of addiction treatment.
Jennifer McNeely, Andrea B. Troxel, Hillary V. Kunins, Donna Shelley, Joshua D. Lee, Alexander Walley, Zoe M. Weinstein, John Billings, Nichola J. Davis, Roopa Kalyanaraman Marcello, Bruce R. Schackman, Charles Barron, Luke Bergmann   +12 more
doaj   +1 more source