Results 71 to 80 of about 53,250,665 (341)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

“Early in the morning, there’s tolerance and later in the day it disappears” – The intersection of resource scarcity, stress and stigma in mental health and substance use care in South Africa

Cambridge Prisms: Global Mental Health
Stress is a challenge among non-specialist health workers worldwide, particularly in low-resource settings. Understanding and targeting stress is critical for supporting non-specialists and their patients, as stress negatively affects patient care ...
Abigail C. Hines, Alexandra L. Rose, Kristen S. Regenauer, Imani Brown, Kim Johnson, Jessica Bonumwezi, Sibabalwe Ndamase, Nonceba Ciya, Jessica F. Magidson, Bronwyn Myers   +9 more
doaj   +1 more source

Exposure to E-Cigarette Advertising and Its Association With E-Cigarette Use Among Youth and Adolescents in Two Largest Cities in Vietnam 2020

Tobacco Use Insights, 2023
BACKGROUND E-cigarette products have become more popular due to the marketing campaigns on various sources but caused adverse health impacts to users, especially adolescents and youths. This paper aims to describe the situation of exposure to e-cigarette
Thi Thanh Huong Le, Tu Hoang Le, Minh Dat Le, Tien Thang Nguyen   +3 more
doaj   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

The Impacts of Supervised Exercise Intervention on Tobacco Withdrawal Symptoms

Tobacco Use Insights, 2023
This study examined a supervised moderate-intensity aerobic exercise programme’s effectiveness in regulating the Tobacco Withdrawal Symptoms (TWS) during temporary abstinence. This was a single group, pre and post-quasi intervention study.
Nur-Hasanah Ruslan, Siti Munira Yasin, Nadzimah Mohd Nasir, Mohamad Rodi Isa   +3 more
doaj   +1 more source

Development of a Coding Instrument to Assess the Quality and Content of Anti-Tobacco Video Games [PDF]

, 2015
Previous research has shown the use of electronic video games as an effective method for increasing content knowledge about the risks of drugs and alcohol use for adolescents.
Alber, Julia M., Barnett, Tracey E., Bernhardt, Jay M., Mercado, Rebecca, Watson, Anna M.   +4 more
core   +1 more source

Long‐Term Opioids in Gout: A Matched Cohort Study From the Veterans Health Administration

Arthritis Care &Research, EarlyView.
Objective Though used frequently to treat flare, risk of long‐term opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed long‐term opioids over time.
Lindsay N. Helget, Bryant R. England, Punyasha Roul, Harlan Sayles, Tuhina Neogi, James R. O'Dell, Joshua F. Baker, Ted R. Mikuls   +7 more
wiley   +1 more source

A stakeholder-driven approach to designing a peer recovery coach role for implementation in community-oriented primary care teams in South Africa

Addiction Science & Clinical Practice
Introduction In South Africa, community-oriented primary care teams work to re-engage out-of-care people with HIV (PWH) in treatment, many of whom have substance use (SU) concerns.
Bronwyn Myers, Kristen S. Regenauer, Kim Johnson, Imani Brown, Alexandra L. Rose, Nonceba Ciya, Sibabalwe Ndamase, Yuche Jacobs, Morgan S. Anvari, Abigail Hines, Dwayne Dean, Rithika Baskar, Jessica F. Magidson   +12 more
doaj   +1 more source

Predicting Smoking Behaviors Among Junior High School Students in Ghana [PDF]

, 2018
Despite the rising rate of smoking in sub-Sahara African countries, measures to control the tobacco epidemic have been limited to developed countries.
Sofo, S. (Seidu), Thompson, E. (Emmanuel)   +1 more
core   +2 more sources

Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care

Arthritis Care &Research, EarlyView.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multidisciplinary team‐based care.
Tarun Sharma, Tyson S. Barrett, Teigan Dwyer, Nancy Campbell, Jessica Heintzinger, Ellen Kraemer, Adam Dore, Susan Manzi   +7 more
wiley   +1 more source