Results 101 to 110 of about 203,459 (318)

Predictors of tuberculosis (TB) and antiretroviral (ARV) medication non-adherence in public primary care patients in South Africa: A cross sectional study [PDF]

, 2013
Background: Despite the downward trend in the absolute number of tuberculosis (TB) cases since 2006 and the fall in the incidence rates since 2001, the burden of disease caused by TB remains a global health challenge.
A Kwara, AJ Claxton, BN Muture, Bomkazi Tutshana, DF Marks, DK Freeborn, E Ross, EL Corbett, G Andrews, G Spies, Gladys Matseke, Gugu Mchunu, HS Friedman, IB Corless, J Morgenstern, JB Saunders, Julia Louw, K Peltzer, Karl Peltzer, KS Ingersoll, L Li, L Myer, M Mindachew, M Zuckerman, MA Thompson, MG Amuha, MK Gebremariam, N Chishinga, P Farmer, P Naidoo, PA McInerney, Pamela Naidoo, R Kessler, RAR Gurung, RC Kessler, RT Brooks, SA Munro, SC Kalichman, South African National AIDS Council (SANAC) report, SS Shinn, T Santha, TF Babor, UNAIDS, V Nevarro, World Health Organization, World Health Organization (WHO), Y Hirsch-Moverman   +46 more
core   +2 more sources

Functional Neurocircuits and Neuroimaging Biomarkers of Tobacco Use Disorder [PDF]

Trends in Molecular Medicine, 2018
Drug abuse and addiction remain major public health issues, exemplified by the opioid epidemic currently devastating the United States. Treatment outcomes across substance use disorders remain unacceptably poor, wherein drug discovery/development for this multifaceted neuropsychiatric disorder focuses on single molecular-level targets.
Matthew T, Sutherland, Elliot A, Stein
openaire   +2 more sources

A Minimally Invasive Framework Reveals Region‐Specific Cerebrovascular Remodeling in Aging Using Intravital Functional Ultrasound Imaging and Ultrasound Localization Microscopy (fUS‐ULM)

Advanced Science, EarlyView.
A high‐resolution intravital imaging platform combining functional ultrasound and localization microscopy enables longitudinal, minimally invasive assessment of cerebrovascular function in aging studies. The present investigation reveals aging‐related reductions in neurovascular coupling, arteriole‐to‐venule ratio and vascular density, introducing a ...
Sharon Negri, Adam Nyul‐Toth, Madison Milan, Eva Troyano‐Rodriguez, Sherwin Tavakol, Jennifer Ihuoma, Zeke Reyff, Rakesh Rudraboina, Rafal Gulej, Raymond Jang, Anna Csiszar, Zoltan Ungvari, Audrey Cleuren, David R Miller, Andriy Yabluchanskiy, Mickael Tanter, Stefano Tarantini   +16 more
wiley   +1 more source

Data Mining by Soft Computing Methods for The Coronary Heart Disease Database [PDF]

, 2008
For improvement of data mining technology, the advantages and disadvantages on respective data mining methods should be discussed by comparison under the same condition. For this purpose, the Coronary Heart Disease database (CHD DB) was developed in 2004,
Hara, Akira, Ichimura, Takumi
core  

Declines in prevalence of adolescent substance use disorders and delinquent behaviors in the USA: A unitary trend? [PDF]

, 2017
BackgroundDownward trends in a number of adolescent risk behaviors including violence, crime, and drug use have been observed in the USA in recent years.
Agrawal, Arpana, Bierut, L. J, Bongu, J., Cavazos-Rehg, P. A, Grucza, R. A, Krauss, M. J, Krueger, R. F, Plunk, A. D   +7 more
core   +2 more sources

ADA2 Forms Nuclear Condensates with GCN5 and ATP‐Citrate Lyase (ACL) to Modulate H3K9 Acetylation at Genes Functioning in Rice Meristems

Advanced Science, EarlyView.
This study unveils a novel GAA (GCN5‐ADA2‐ACL) complex that forms nuclear condensates to boost local acetyl‐CoA, facilitating histone acetylation and gene transcription in rice meristems. The research underscores the role of ADA2's disordered region in complex condensation and ACL's role in acetyl‐CoA production.
Yaping Yue, Tingting Lu, Xiaoyuan Guo, Biao Liu, Shiteng Lv, Heba A. M. Abdalla, Xuelei Lai, Ruihui Zhang, Jianpin Guo, Yu Zhao, Dao‐Xiu Zhou, Shaoli Zhou   +11 more
wiley   +1 more source

Low Dopamine D2/D3 Receptor Availability is Associated with Steep Discounting of Delayed Rewards in Methamphetamine Dependence. [PDF]

, 2015
BackgroundIndividuals with substance use disorders typically exhibit a predilection toward instant gratification with apparent disregard for the future consequences of their actions.
Ballard, Michael E, Dean, Andy C, Hsu, Eustace, Ishibashi, Kenji, London, Edythe D, Mandelkern, Mark A, Monterosso, John R, Robertson, Chelsea L   +7 more
core   +3 more sources

Gut Microbe‐Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

Advanced Science, EarlyView.
Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.
Ningbo HuangFu, Xiangzhen Zhu, Zhijuan Tang, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Jinjie Cui, Zhaojiang Guo, Junyu Luo, Xueke Gao   +10 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Prevalence and variables associated with alcohol and tobacco consumption in burned patients

Archivo Médico de Camagüey, 2020
Background: current studies have showed that there is a high prevalence of alcohol and tobacco use in burned patients. In Cuba, published research on this topic is scarce.
Malvin Rodríguez-Vargas
doaj