Results 141 to 150 of about 206,627 (318)
The classification of substance and behavioural addictions: A preliminary investigation [PDF]
, 2012 The term addiction has been used to refer to impaired control over substance use for several centuries however recently there has been a shift toward using this term in the context of non-substance use disorders, such as pathological gambling.
McLaughlan, Andre David +1 more
core +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee +5 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective To synthesize the evidence on the associations between vegetarian and/or vegan diets (VVDs) and symptoms of orthorexia nervosa (ON) compared with omnivorous diets in the adult population. Method Following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) and the Meta‐analyses of Observational Studies in ...
Valentina Díaz‐Goñi +9 more
wiley +1 more source
Forecasting heart failure: Seasonal alignment of heart failure outcomes in New York
ESC Heart Failure, Volume 12, Issue 2, Page 819-831, April 2025.Abstract Background Seasonal variations have been observed in heart failure (HF) hospitalization. Numerous explanatory mechanisms have been proposed, but no prior studies have examined potential contributors directly. Our objective was to identify specific factors that could contribute to seasonal variability using a large longitudinal dataset of HF ...
Prerna Gupta +5 more
wiley +1 more source
Olanzapine Attenuates Cue-elicited Craving for Tobacco
, 2004 Rationale: Recent biological conceptualizations of craving and addiction have implicated mesolimbic dopamine activity as a central feature of the process of addiction. Imaging, and pharmacological studies have supported a role for dopaminergic structures
Hutchinson, Kent E +5 more
core
Comparing teen substance use in northern New Hampshire to rural use nationwide [PDF]
, 2013 Using data administered in 2011 from the Carsey Institute’s Coös Youth Study and the National Survey on Drug Use and Health, this brief compares teen substance use patterns in New Hampshire’s most rural county to patterns among rural youth nationwide ...
Van Gundy, Karen T.
core +1 more source
Environmental and Molecular Mutagenesis, EarlyView.Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons +17 more
wiley +1 more source
Introduction to Special Issue on Tobacco and Other Substance Use Disorders: Links and Implications [PDF]
, 2016 Theresa Winhusen
openalex +1 more source
European Eating Disorders Review, EarlyView.ABSTRACT Objective This study investigates clinical heterogeneity in patients with binge eating disorder (BED) and its association with treatment outcomes. Methods A two‐step cluster analysis was conducted on a clinical sample of 196 BED patients, using an agglomerative hierarchical procedure based on both categorical and quantitative measures ...
Lucía Camacho‐Barcia +10 more
wiley +1 more source