Results 81 to 90 of about 187,006 (336)
People affected by psychotic, depressive and developmental disorders are at a higher risk for alcohol and tobacco use. However, the further associations between alcohol/tobacco use and symptoms/cognition in these disorders remain unexplored.
Ling Qiu+13 more
doaj +1 more source
Abandonment of nicotine dependence treatment: A cohort study
CONTEXT AND OBJECTIVE: Non-adherence to treatment is one of the hindering factors in the process of smoking cessation. This study aimed to compare sociodemographic characteristics, smoking status and motivation among smokers who maintained or abandoned ...
Maritza Muzzi Cardozo Pawlina+3 more
doaj +1 more source
This study tested associations between observed neighborhood physical disorder and tobacco use, alcohol binging, and sugar-sweetened beverage consumption among a large population-based sample from an urban area of the United States. Individual-level data
Jesse J. Plascak+7 more
doaj
Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease
The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su+12 more
wiley +1 more source
Substance Use and Depression Symptomatology: Measurement Invariance of the Beck Depression Inventory (BDI-II) among Non-Users and Frequent-Users of Alcohol, Nicotine and Cannabis [PDF]
Depression is a highly heterogeneous condition, and identifying how symptoms present in various groups may greatly increase our understanding of its etiology.
Moore, Ashlee A.+3 more
core +4 more sources
Assessment of Alcohol and Tobacco Use Disorders Among Religious Users of Ayahuasca
The aims of this study were to assess the impact of ceremonial use of ayahuasca—a psychedelic brew containing N,N-dimethyltryptamine (DMT) and β-carboline —and attendance at União do Vegetal (UDV) meetings on substance abuse; here we report the findings ...
Paulo Cesar Ribeiro Barbosa+7 more
doaj +1 more source
Real‐time NMR spectroscopy is used to study JNK1‐dependent phosphorylation of the intrinsically disordered substrate JIP1, revealing eleven phosphosites with distinct phosphorylation efficiencies. The site‐specific phosphorylation rates are shown to be determined by both the sequence position of the phosphosites relative to the two kinase docking site ...
Thibault Orand+7 more
wiley +1 more source
Barriers to treatment of alcohol and tobacco use disorders in industrial workers
Background: Substance use disorders (SUDs) are common among industrial workers and often lead to higher absenteeism and lower productivity. Multiple factors may be responsible for hindering the treatment of SUDs among industrial workers.
Sachdeva, Ankur+2 more
openaire +2 more sources
Predictors of subgroups based on maximum drinks per occasion over six years for 833 adolescents and young adults in COGA. [PDF]
ObjectiveA person's pattern of heavier drinking often changes over time, especially during the early drinking years, and reflects complex relationships among a wide range of characteristics.
Agrawal, Arpana+10 more
core +1 more source
This study found that 54% of elderly inpatients were prescribed at least one potentially inappropriate medication (PIM) based on the 2023 AGS Beers Criteria. Among identified PIMs, 32.2% were medications to avoid, and 52.8% required cautious use. Polypharmacy and chronic kidney disease (CKD) were key predictors of PIM use.
Subash Karki+2 more
wiley +1 more source