Comparison of Transdermal Nitroglycerine Patch and Oral Nifedipine for Tocolysis in Preterm Labour: A Prospective Interventional Study [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Preterm labour and delivery have a major contribution to perinatal mortality and morbidity. Tocolytic therapy reduces neonatal mortality and morbidity by prolonging gestation, allowing for corticosteroid administration and in-utero transfer
Kalpana Kumari +6 more
doaj +1 more source
Detection of fetal fibronectin in twin pregnancies in relation to gestational age [PDF]
, 1999 CONTEXT: The presence of fetal fibronectin in the cervix or vagina has been investigated as a possible marker for the risk of preterm birth. Fetal fibronectin in cervical fluid can provide direct evidence of pathologic changes at the interface of fetal ...
Camano, Luiz +4 more
core +3 more sources
PDE4 as a target in preterm labour. [PDF]
, 2007 : Cyclic nucleotide phosphodiesterases (PDE) are the enzymes catalyzing the hydrolysis and inactivation of the second messengers, cAMP and cGMP. Eleven PDE families are described to date, and selective inhibitors of some PDEs families are currently used ...
Céline Méhats +18 more
core +5 more sources
The roles of Prostanoid EP receptors in the control of contractions of human myometrium
, 2012 The primary function of the uterus during pregnancy is to harbour the growing fetus in a quiescent environment. Upon maturation of the fetus, the uterus generates forceful contractions during labour. Prostaglandins are central in the parturition process.
Arulkumaran, Shankari +1 more
core +1 more source
Progestogens in singleton gestations with preterm prelabor rupture of membranes: a systematic review and metaanalysis of randomized controlled trials [PDF]
, 2018 OBJECTIVE DATA: Preterm prelabor rupture of membranes occurs in 3% of all pregnancies. Neonatal benefit is seen in uninfected women who do not deliver immediately after preterm prelabor rupture of membranes.
Berghella, Vincenzo +5 more
core +1 more source
Progesterone and Preterm Birth Prevention: Translating Clinical Trials Data into Clinical Practice [PDF]
, 2012 OBJECTIVE: We sought to provide evidence-based guidelines for using progestogens for the prevention of preterm birth (PTB). METHODS: Relevant documents, in particular randomized trials, were identified using PubMed (US National Library of Medicine, 1983
Berghella, Vincenzo
core +1 more source
Implementation of foetal fibronectin testing: Admissions, maternal interventions and costs at 1 year [PDF]
, 2016 Foetal fibronectin testing (fFN) has a high negative predictive value for preterm delivery, but it has a cost implication. This two-stage prospective study evaluated the real patient costs and clinical impact of introducing the fFN test in women ...
Currie, J +4 more
core +1 more source
Serum estradiol (E2), progesterone (P), and human chorionic gonadotropin (HCG), D-dimer (D-D) fibrinogen (FIB) levels after low molecular weight heparin sodium on preventing miscarriage in patients with adverse pregnancy and delivery [PDF]
Journal of Medical BiochemistryBackground: This study investigates the effects of subcutaneous injection of low molecular weight heparin (LMWH) sodium on preventing miscarriage in patients with adverse pregnancy and delivery. Specifically, it evaluates changes in serum estradiol (E2),
Pei Liucheng, Wang Ting, Yang Qiuling
doaj +1 more source
Clinical aspects of cervical insufficiency [PDF]
, 2007 Fetal loss is a painful experience. A history of second or early third trimester fetal loss, after painless dilatation of the cervix, prolapse or rupture of the membranes, and expulsion of a live fetus despite minimal uterine activity, is characteristic ...
Lotgering Frederik K
core +1 more source
Taiwanese Journal of Obstetrics & Gynecology, 2016 Objective: Neutropenia developed after continuous intravenous infusion of ritodrine hydrochloride (Yutopar) for preterm uterine contractions in a twin pregnancy.
Chen-Yu Wang +6 more
doaj +1 more source