Results 11 to 20 of about 5,304 (227)

Tocolytic agents and the failure to improve neonatal outcomes

Pregnancy
Premature delivery has long been a major problem in obstetrics. Increased perinatal morbidity and mortality as well as substantial health care costs, both short and long term, have driven the efforts to combat this complication.
Jack FitzSimmons, Emily Oliver
doaj   +2 more sources

School Performance After Maintenance Tocolysis With Nifedipine for Threatened Preterm Birth: 12-Year Follow-Up of the APOSTEL 2 Trial. [PDF]

BJOG
ABSTRACT Objective To evaluate school performance at 12 years of age in children prenatally exposed to maintenance tocolysis with nifedipine versus placebo. Design 12‐year follow‐up of the multicentre APOSTEL 2 trial, in which participants with threatened preterm birth between 26+0 and 32+2 weeks of gestation, who remained pregnant after initial 48‐h ...
van der Windt LI, Meliezer JAL, Pajkrt E, Spaanderman MEA, Scheepers HCJ, Mol BW, Oudijk MA, Ravelli ACJ, Roos C.   +8 more
europepmc   +2 more sources

The Experience and Outcomes of Rescue Cervical Cerclage at a Victorian Tertiary Hospital-A Retrospective Observational Study. [PDF]

Aust N Z J Obstet Gynaecol
ABSTRACT A rescue cervical cerclage is an emergency procedure aimed to prolong pregnancy and reduce the risk of preterm birth for women with an open cervix. This retrospective study assessed risk factors, perioperative management and outcomes for all attempted rescue cerclage over 3 years in a large tertiary hospital in Australia.
Phung M, Dawes L.
europepmc   +2 more sources

Monopolar Single Tip Radiofrequency as Treatment of Giant Placental Chorioangioma. [PDF]

Prenat Diagn
Prenatal Diagnosis, Volume 46, Issue 4, Page 543-545, April 2026.
Dumery G, Megier C, Luton D, Baron X, Dhombres F, Joseph Vivanti A, Maurice P.   +6 more
europepmc   +2 more sources

Facility-Level Factors Associating Antenatal Corticosteroid Administration Rates and Subsequent Term Birth Rates: A Nationwide Cross-Sectional Observational Study Using the 2020-2022 Perinatal Registry Database in Japan. [PDF]

J Obstet Gynaecol Res
ABSTRACT Aim The antenatal corticosteroid (ACS) administration rate in Japan is low. To achieve both high coverage and low overtreatment of ACS, understanding of facility‐level factors is important. This study aimed to identify facility‐level factors associated with ACS coverage and overtreatment and simulate the potential consequences of increased ACS
Fuma K, Ushida T, Imaizumi T, Tano S, Matsuo S, Katsuki S, Imai K, Kajiyama H, Kotani T.   +8 more
europepmc   +2 more sources

Using tocolysis in pregnant women with symptomatic placenta praevia does not significantly improve prenatal, perinatal, neonatal and maternal outcomes: a systematic review and meta-analysis

Systematic Reviews, 2018
Background Placenta praevia refers to a placenta located in the lower segment of the uterus. This abnormal location predisposes the placenta to abnormal bleeding with an increased risk of premature labour.
Frederick Morfaw, Mercy Fundoh, Jessica Bartoszko, Lawrence Mbuagbaw, Lehana Thabane   +4 more
doaj   +1 more source

Combined uterorelaxant effect of magnesium sulfate and terbutaline: Studies on late pregnant rat uteri in vitro and in vivo

Acta Obstetricia et Gynecologica Scandinavica, 2023
Introduction Preterm delivery and its complications are among the biggest challenges and health risks in obstetrical practice. Several tocolytic agents are used in clinical practice, although the efficacy and side effect profiles of these drugs are not ...
Tamara Barna, Kalman F. Szucs, Annamaria Schaffer, Mohsen Mirdamadi, Judit Hajagos‐Toth, Robert Gaspar   +5 more
doaj   +1 more source

Differences between evidence-based recommendations and actual clinical practice regarding tocolysis: a prospective multicenter registry study

BMC Pregnancy and Childbirth, 2018
Background International guidelines recommend that tocolytic therapy be restricted to a single 48-h application. However, multiple cycles of tocolytic therapy and maintenance therapy that exceeds 48 h appear to play a role in daily clinical practice.
Emina Nazifovic, Heinrich Husslein, Ioana Lakovschek, Florian Heinzl, Elisabeth Wenzel-Schwarz, Philipp Klaritsch, Ekrem Kilic, Sarah Hoesel, Rudolf Bind, Magdalena Pabinger, Harald Zeisler, Lorenz Kuessel   +11 more
doaj   +1 more source

Progesterone and nifedipine for maintenance tocolysis after arrested preterm labor: A systematic review and meta-analysis of randomized controlled trial

Taiwanese Journal of Obstetrics & Gynecology, 2016
Objective: No treatment is recommended for routine maintenance tocolysis after an arrested preterm birth. Our present study aimed to evaluate the effect of progesterone and nifedipine as maintenance tocolysis therapy after an arrested preterm birth ...
Ming-Xia Ding, Xin Luo, Xue-Mei Zhang, Bing Bai, Ju-Xiang Sun, Hong-Bo Qi   +5 more
doaj   +1 more source

Unit policies regarding tocolysis after preterm premature rupture of membranes: association with latency, neonatal and 2-year outcomes (EPICE cohort)

Scientific Reports, 2020
After preterm premature rupture of membranes (PPROM), antibiotics and antenatal steroids are effective evidence-based interventions, but the use of tocolysis is controversial.
Elsa Lorthe, Carla Moreira, Tom Weber, Lene D. Huusom, Stephan Schmidt, Rolf F. Maier, Pierre-Henri Jarreau, Marina Cuttini, Elizabeth S. Draper, Jennifer Zeitlin, Henrique Barros, The EPICE research group   +11 more
doaj   +1 more source