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Arrest of mouse preterm labor until term delivery by combination therapy with atosiban and mundulone, a natural product with tocolytic efficacy [PDF]
There is a lack of FDA-approved tocolytics for the management of preterm labor (PL). In prior drug discovery efforts, we identified mundulone and mundulone acetate (MA) as inhibitors of in vitro intracellular Ca2+-regulated myometrial contractility.
Shajila Siricilla +12 more
doaj +2 more sources
Background The use of tocolytic hospitalization in antenatal care is controversial and worthy of more research. We investigated individual, institutional, and area factors that affect the use of tocolytic hospitalizations in Taiwan where fertility has ...
Tsai Eing-Mei +3 more
doaj +1 more source
Background. Obesity is associated with the risk of spontaneous preterm birth. Hexoprenaline is the effective and most widely used tocolytic agent, possessing however a significant number of side effects.
L. V. Gureeva +3 more
doaj +1 more source
Tocolytic plant Tectona grandis Linn. extended study on other systemic effect.
Introduction: Tectona grandis Linn. (T.G) is one of the well-known Indian herbs. In Ayurveda, T.G stem extract has tocolytic effect. Our previous study conformed the tocolytic activity of the T.G stem extract on rat uterine contraction.
Deepali Laxman Jaybhaye +4 more
doaj +1 more source
Southeast Nigerian polyherbal (AJUMBISE): A potential uterotonic and tocolytic agents
Ajumbise is a polyherbal used by women in southeast Nigeria to enhance labor, expel retained placenta and blood clots after delivery, relief postpartum and menstrual pains and promote involution of the uterus.
S.N. Ijioma +4 more
doaj +1 more source
Background A few studies have reported that maternal administration of antenatal corticosteroids increased the risk of pulmonary edema (PE). However, despite the increasing usage rate of betamethasone as antenatal corticosteroid, maternal administration ...
Takashi Nishikawa, Ken Fukuhara
doaj +1 more source
Objective: To compare the efficacy of atosiban with conventional treatment of the threatened preterm labor. Materials and methods: All the data of pregnant women with threatened preterm labor from January 1 to December 31, 2017, who received atosiban ...
Yan Yu +4 more
doaj +1 more source
Antenatal dexamethasone for late preterm delivery: Rate of complete course and neonatal outcomes
Abstract Objective This retrospective cohort study aimed to assess the rate of complete dexamethasone administration among late preterm deliveries and its impact on neonatal outcomes. Methods We reviewed medical records of 1500 late preterm deliveries (gestational age 34–36 + 6 weeks) between January 2018 and December 2020, analyzing baseline ...
Piyamon Srisakulpanich +3 more
wiley +1 more source
Spontaneous preterm birth is one of the most pressing issues in obstetrics, as it remains one of the leading causes of newborn morbidity and mortality.
E. A. Sоkоvа +3 more
doaj +1 more source
Maternal pulmonary edema after 46 h of ritodrine hydrochloride administration: A case report
Introduction: Ritodrine hydrochloride is still widely used as a tocolytic agent in Japan, but it can cause maternal pulmonary edema, which may paradoxically induce preterm birth. Here we present a case of severe pulmonary edema due to
Tsuyoshi Murata +7 more
doaj +1 more source

