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The Oxytocin-Oxytocin Receptor System and Its Antagonists as Tocolytic Agents [PDF]

open access: goldInternational Journal of Endocrinology, 2011
Oxytocin, a hormone involved in numerous physiologic processes, plays a central role in the mechanisms of parturition and lactation. It acts through its receptor, which belongs to the G-protein-coupled receptor superfamily, while Gq/phospholipase C (PLC)/
Nikolaos Vrachnis   +4 more
doaj   +2 more sources

Tocolytic Therapy Inhibiting Preterm Birth in High-Risk Populations: A Systematic Review and Meta-Analysis [PDF]

open access: goldChildren, 2023
This systematic review aimed to identify the benefits and possible harms of tocolytic therapy for preterm labour management in the context of pregnant women with extremely preterm birth, multiple gestations, or growth-restricted foetuses. A comprehensive
Noyuri Yamaji   +9 more
doaj   +2 more sources

Tocolytic effect of the monoterpenic phenol isomer, carvacrol, on the pregnant rat uterus

open access: goldChinese Journal of Physiology, 2020
Despite the wide application of carvacrol (CAR) in different biological and medical areas, there is still insufficient electrophysiological data on the mechanisms of action of CAR, particularly in the pregnant uterine function.
Victor Manuel Munoz-Perez   +4 more
doaj   +2 more sources

In vitro study of the tocolytic effect of oroxylin A from Scutellaria baicalensis root [PDF]

open access: diamondJournal of Biomedical Science, 2009
Scutellariae Radix is one of the well-known tocolytic Chinese herbs. Oroxylin A is isolated from the root of Scutellaria baicalensis. The main syndrome of preterm birth is caused by uterus contractions from excitatory factors. Administration of tocolytic
Yang Ling-Ling   +2 more
doaj   +2 more sources

Lemongrass Alleviates Primary Dysmenorrhea Symptoms by Reducing Oxidative Stress and Inflammation and Relaxing the Uterine Muscles [PDF]

open access: yesAntioxidants
Primary dysmenorrhea (PD) is characterized by lower abdominal spasms and painful cramps during menstruation in females with a normal pelvic anatomy. Cymbopogon citratus (DC.) Stapf, commonly known as lemongrass, is consumed in the form of herbal tea ...
Sheikh Safeena Sidiq   +7 more
doaj   +2 more sources

Gauging the safety and efficacy of nitroglycerine used transdermally as a tocolytic agent in females with preterm labor

open access: diamondMuller Journal of Medical Sciences and Research
Background: Preterm labor is the primary challenge in prenatal health care, leading to a high rate of mortality. As a result, in pregnant women with preterm labor, we use nitroglycerine transdermally as a tocolytic agent. The main objective of this study
Anand Tambat   +2 more
doaj   +2 more sources

BRONCHODILATOR AND TOCOLYTIC FEATURES OF β2-ADRENOCEPTOR AGONISTS

open access: greenРазработка и регистрация лекарственных средств, 2019
The issues (aspects) of bronchodilator and tocolytic actions of β₂-adrenoceptor agonists are reviewed. The data on short-acting and new long-acting β₂-agonists are presented.
S. Ya. Skachilova   +3 more
doaj   +1 more source

A historical narrative review through the field of tocolysis in threatened preterm birth [PDF]

open access: yesEuropean Journal of Obstetrics & Gynecology and Reproductive Biology: X
Preterm birth presents a significant challenge in clinical obstetrics, requiring effective strategies to reduce associated mortality and morbidity risks.
Tijn van Winden   +4 more
doaj   +2 more sources

Maternal serum interleukin 6 and 8 and C-reactive protein in predicting the tocolytic therapy in preterm labor

open access: greenJournal of Research in Medical Sciences, 2014
Background: This study aimed to evaluate the relation between C-reactive protein (CRP), interleukin (IL) 6 and 8 with the response to tocolytic therapy.
Zahra Shahshahan   +2 more
doaj   +2 more sources

Effect of ADRB gene polymorphism on the efficacy and safety of tocolytic therapy with β2-adrenergic agonists in preterm birth [PDF]

open access: greenРМЖ. Мать и дитя, 2020
G.F. Proklova1, R.A. Chilova1, E.A. Sokova2, R.E. Kazakov2, E.V. Zhukova1, K.O. Akopov3, N.S. Trifonova1 1I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation 2Scientific Centre for Expert ...
G.F. Proklova   +5 more
doaj   +1 more source

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