Results 61 to 70 of about 4,209 (214)

Structure–Activity Relationship Study on Ligands Activating the Voltage‐Gated Potassium Channel KV7.1

open access: yesArchiv der Pharmazie, Volume 359, Issue 6, June 2026.
Activation of the voltage gated K+ channel KV7.1 leads to hyperpolarization shift of cell membranes. In a thorough SAR study eight positions of the lead compound (R)‐L3 were modified. (R)‐configuration, the indolylmethyl moiety in 3‐position and the 2‐fluorophenyl moiety in 5‐position appeared to be essential for high KV7.1 activation, whereas an OH ...
Florian Roßner   +3 more
wiley   +1 more source

Tocolytic effectiveness of nifedipine versus ritodrine and follow-up of newborns: a randomised controlled trial

open access: yes, 2008
BACKGROUND: Several studies have demonstrated the superior tocolytic effectiveness of nifedipine over ritodrine. Only 1 trial conducted a long-term follow-up of newborns and found no difference in psychosocial and motor functioning.
Water, van de, M.   +7 more
core   +1 more source

External cephalic version outcomes with tocolysis and sedation: A 10‐year retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 173, Issue 3, Page 1343-1351, June 2026.
Abstract Objective To evaluate the effectiveness and safety of external cephalic version (ECV) performed with tocolysis and sedation or spinal anesthesia, and to identify predictors of ECV success, complications, and delivery outcomes after successful ECV. Methods This 10‐year cohort study included 990 pregnant women with term non‐cephalic presentation
Javier Sánchez‐Romero   +7 more
wiley   +1 more source

Tocolytic Effect of the Cyclooxygenase-2 Inhibitor, Meloxicam: Studies on Uterine Contractions in the Rat

open access: yes, 1998
The objective of this study was to assess the tocolytic activity of meloxicam, a novel cyclooxygenase-2 inhibitor, in a comparative study with the non-steroidal anti-inflammatory drug, indomethacin.
Mariam H Yousif, Olav Thulesius
core   +1 more source

Perinatal outcomes associated with magnesium sulfate for preeclampsia without severe features

open access: yesPregnancy, Volume 2, Issue 3, May 2026.
Abstract Objective To evaluate neonatal outcomes in patients with preeclampsia without severe features who received magnesium for seizure prophylaxis. Methods Retrospective cohort study of patients with preeclampsia without severe features delivering ≥32 weeks’ gestation at our institution (November 2021–May 2023).
Samantha E. Howell   +8 more
wiley   +1 more source

Updated WHO recommendations on antenatal corticosteroids and tocolytic therapy for improving preterm birth outcomes

open access: yes, 2022
Updated WHO recommendations on antenatal corticosteroids and tocolytic therapy for improving preterm birth ...
ZP Qureshi (14628584)   +6 more
core  

Contraction frequency and acidemia at birth: A case–control study

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 5, Page 904-911, May 2026.
This case–control study shows an association by exposure level between contraction frequency during the final hour before birth and fetal acidemia. Effect sizes are similar regardless of oxytocin use. Contraction frequencies above both the conventional and revised thresholds are common, indicating poor positive predictive value.
Johanna Wagner Bjurström   +4 more
wiley   +1 more source

Preliminary Study : Comparison of the Efficacy of Progesterone and Nifedipine in Inhibiting Threatened Preterm Labour in Siriraj Hospital

open access: yesThai Journal of Obstetrics and Gynaecology, 2009
Objective: To compare the efficacy, success rate, maternal and fetal complications of progesterone and nifedipine administration as a tocolytic agent to women with threatened preterm labour. Study Design : A randomized controlled trial.
Saifon Chawanpaiboon   +4 more
doaj  

The effect of labor epidural analgesia on uterine activity using electrohysterography monitoring: A follow‐up study

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 5, Page 912-921, May 2026.
Epidural analgesia during the first stage of labor shows no clinically relevant changes in uterine contraction frequency and duration, but it is associated with a significant reduction in uterine intensity. Their clinical implications need further research.
Phebe B. Q. Berben   +10 more
wiley   +1 more source

Management of preterm labor: atosiban or nifedipine?

open access: yesInternational Journal of Women's Health, 2010
Roel de Heus, Eduard J H Mulder, Gerard H A VisserDepartment of Woman and Baby, University Medical Centre Utrecht, The NetherlandsAbstract: Preterm birth is strongly associated with neonatal death and long-term neurological morbidity.
Roel de Heus   +2 more
doaj  

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