Results 121 to 130 of about 414,505 (390)

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source

Pseudomonas toe web infection and autosensitisation dermatitis: Diagnostic and therapeutic challenge [PDF]

, 2020
Jae Wan Park, Guk Jin Jeong, Seong Jun Seo, Kapsok Li   +3 more
openalex   +1 more source

Generalised agent for solving higher board states of tic tac toe using Reinforcement Learning [PDF]

, 2022
Bhavuk Kalra
openalex   +1 more source

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

A study of the relative stability of the motor quotient in the high school girl [PDF]

, 1950
Thesis (Ed.M.)--Boston ...
MacNabo, Margaret M
core   +1 more source

Three Synchronized, Miniaturized, Wireless Inertial Measurement Unit Sensors for Automated Gait and Balance Analysis System

Advanced Intelligent Systems, EarlyView.
This study presents a compact, three IMU wearable system that enables accurate motion capture and robust gait‐feature extraction, thereby supporting reliable machine learning‐based balance evaluation. Accurate assessment of balance is critical for fall prevention and targeted rehabilitation, particularly in older adults and individuals with ...
Seok‐Hoon Choi, Ki‐Hoon Kim, Heung Jin Park, Yuna Kim, Hyunjin Lee, Yu Bin Lee, Youn Joung Kang, Sungchul Huh, Min‐Ho Seo   +8 more
wiley   +1 more source

Editorial: Grammar in the face of diversity [PDF]

, 2006
The river one dips one’s toes into from one editorial to the next is never the same, as Heraclitus might have observed. Part 1 of this double issue (December, 2005) consisted of eight articles from contributors based in five countries: the United States,
Locke, Terry
core  

Prevalence of floating toe and its relationship with static postural stability in children: The Yamanashi adjunct study of the Japan Environment and Children’s Study (JECS-Y)

, 2021
Taro Fujimaki, Masanori Wako, Kensuke Koyama, Naoto Furuya, Ryoji Shinohara, Sanae Otawa, Anna Kobayashi, Sayaka Horiuchi, Megumi Kushima, Zentaro Yamagata, Hirotaka Haro, on behalf of The Yamanashi adjunct study of the Japan Environment and Children’s Study Group   +11 more
openalex   +1 more source

Planning and Control Framework for a Quadruped Robot With Changeable Configuration

Advanced Intelligent Systems, EarlyView.
Multiconfiguration quadruped robots enhance adaptability by switching between mammal‐like and reptile‐like morphologies. This study presents a nonlinear constraint‐based motion planner integrated with a hierarchical whole‐body controller, enabling robust configuration switching and locomotion on complex terrains. Experiments on slopes, irregular bricks,
Guanglin Lu, Yifan Zhang, Teng Chen, Xuewen Rong, Guoteng Zhang, Yibin Li   +5 more
wiley   +1 more source