Results 91 to 100 of about 49,935 (237)

Paradoxical Alopecia Areata Induced by IL‐17 and IL‐23 Inhibitors: A Systematic Review

JEADV Clinical Practice, EarlyView.
This systematic review identifies consistent clinical patterns of alopecia areata associated with IL‐17 and IL‐23 inhibitors, most frequently involving secukinumab and ustekinumab. Disease severity varied widely, and management often required biologic discontinuation or therapeutic switching.
Isabella Kamholtz, Simonetta I. Gaumond, Joaquin J. Jimenez   +2 more
wiley   +1 more source

Tofacitinib, an oral Janus kinase inhibitor: pooled efficacy and safety analyses in an Australian rheumatoid arthritis population [PDF]

, 2018
In Australia, there is an unmet need for improved treatments for rheumatoid arthritis (RA). Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA.
Soma, Koshika, David Witcombe, Bird, Paul, Peter Nash (473901), Kwok, Kenneth, Paul Bird, Kenneth Kwok, Bossingham, David, Kenneth Kwok (177017), Maureen Rischmueller (51295), Rischmueller, Maureen, David Witcombe (5276288), Thirunavukkarasu, Krishan, Krishan Thirunavukkarasu, Hall, Stephen, Peter Nash, Koshika Soma (5276285), Maureen Rischmueller, Paul Bird (5276291), Nicola Cook (3284883), Koshika Soma, Nash, Peter, David Bossingham (5276297), Witcombe, David, Stephen Hall, Stephen Hall (169258), David Bossingham, Cook, Nicola, Nicola Cook, Krishan Thirunavukkarasu (5276294)   +29 more
core   +1 more source

Therapeutic JAK Inhibition in Idiopathic Subglottic Stenosis

The Laryngoscope, EarlyView.
Three patients with idiopathic subglottic stenosis and rheumatoid arthritis began JAK inhibitor therapy, after which the mean surgical‐free interval between endoscopic dilations rose from 317 to 631 days and the annualized dilation rate fell from 1.24 to 0.38 per patient‐year. Figure 2 shows this as a per‐patient timeline.
Riley M. Larkin, Ioan Lina, Julianna Kostas, Caroline Christmann, Kevin Byram, Alexander Gelbard   +5 more
wiley   +1 more source

Impact of tofacitinib on patient outcomes in rheumatoid arthritis – review of clinical studies

, 2016
Eric G Boyce, Deepti Vyas, Edward L Rogan, Cynthia S Valle-Oseguera, Kate M O'Dell Department of Pharmacy Practice, Thomas J Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA, USAAbstract: Rheumatoid arthritis is a ...
Rogan EL, Boyce EG, Valle-Oseguera CS, O’Dell KM, Vyas D   +4 more
core  

Tofacitinib in combination with methotrexate in patients with rheumatoid arthritis: clinical efficacy, radiographic and safety outcomes from the 24-month phase 3 ORAL scan study

, 2019
Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). The Phase 3, 24-month, placebo-controlled trial, ORAL Scan (NCT00847613), evaluated tofacitinib efficacy, including structural progression, and safety in ...
Roy Fleischmann, Cohen, Stanley, Kremer, Joel, Zerbini, Cristiano A. F., Cardiel, Mario H, Dana Tegzová, Carol A. Connell, Yeong‐Wook Song, Strand, Vibeke, Tanaka, Yoshiya, Vibeke Strand, Gruben, David, Wallenstein, Gene, Keystone, Edward, Mario H. Cardiel, The ORAL Scan Investigators, Joel Kremer, Désirée van der Heijde, Gene Wallenstein, Peter Nash, Connell, Carol A., Stanley Cohen, Song, Yeong-Wook, Yoshiya Tanaka, Connell, Carol A, David Gruben, Edward Keystone, Cristiano A. F. Zerbini, Nash, Peter, Zerbini, Cristiano AF, van der Heijde, Désirée, Stanley Cohen, Stanley, Tegzová, Dana, Cardiel, Mario H., et al., Fleischmann, Roy   +35 more
core   +1 more source

Pregnancy in CTD‐interstitial lung disease: Current evidence, clinical challenges, and a proposed management algorithm

Rheumatology &Autoimmunity, EarlyView.
Summary of pregnancy management in CTD‐ILD across preconception, antenatal, and postpartum phases, emphasizing risk stratification and multidisciplinary care. 6MWT, 6‐min walk test; CTD‐ILD: connective tissue disease‐interstitial lung disease; DLCO, diffusion capacity of the lung for carbon monoxide; FVC, forced vital capacity; MDT, multidisciplinary ...
Khaled Aldhuaina, Ghaydaa Aldabie, Mohammad Abdulsalam, Ali Jawad   +3 more
wiley   +1 more source

Tofacitinib: A Review in Rheumatoid Arthritis

, 2018
Compliance with Ethical StandardsFunding: The preparation of this review was not supported by any external funding.Conflicts of interest: Sohita Dhillon is a salaried employee of Adis/Springer, is responsible for the article content and declares no ...
Sohita Dhillon (4873375)
core   +1 more source

AA Tofacitinib Supplementary Table 1

, 2021
Alopecia areata recurrence patterns in children and young adults while on systemic tofacitinib ...
McKenzie, Paige
core   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Tofacitinib in acute severe ulcerative colitis: review addressing seven key unmet needs

Therapeutic Advances in Gastroenterology
Tofacitinib, an oral Janus kinase (JAK) inhibitor, shows promise as a rescue therapy for acute severe ulcerative colitis (ASUC), a life-threatening condition marked by high colectomy rates.
Chuong Dinh Nguyen, Luan Minh Dang, Thong Duy Vo, Hoang Huu Bui, Eun Soo Kim, Joyce Wing Yan Mak, Choon Jin Ooi   +6 more
doaj   +1 more source