Results 111 to 120 of about 1,815 (184)

Role of fatty liver in the association between obesity and reduced hepatic insulin clearance [PDF]

open access: yes, 2019
新潟大学博士(医学)Aim. – Hepatic insulin clearance (HIC) is important in regulating plasma insulin levels. Diminished HIC causes inappropriate hyperinsulinaemia, and both obesity and fatty liver (FL), which are known to decrease HIC, can be found either together
175208, Matsubayashi, Yasuhiro
core  

Effect of tofogliflozin, a sodium-glucose co-transporter-2 inhibitor, on skeletal muscle mitochondrial function in diabetic mice with muscle atrophy [PDF]

open access: yes
順天堂大学博士(医学)2024年度doctoral ...
スギモト(キシダ), チアキ   +1 more
core  

Nocturia and SGLT2 inhibitors: A review of pathophysiology, clinical evidence, and therapeutic implications

open access: yesContinence
Background: Sodium-glucose cotransporter-2 (SGLT2) inhibitors are widely used in patients with diabetes, heart failure, and chronic kidney disease, all of whom are at elevated risk for nocturia.
Matthew Antonellis   +4 more
doaj   +1 more source

Volume 16

open access: yes
Journal of Diabetes Investigation, Volume 16, Issue 12, Page 2260-2284, December 2025.
wiley   +1 more source

The effects of SGLT2 inhibitors in patients with metabolic dysfunction-associated fatty liver disease; a narrative review [PDF]

open access: yes
Worldwide, metabolic dysfunction-associated fatty liver disease (MAFLD) is a significant public health concern, especially since more than fifty percent of people with type 2 diabetes are affected by it. This pathological condition includes all states of
Bica, Cristina Ioana   +7 more
core   +2 more sources

Effect of combination pioglitazone with SGLT2i or GLP-1 RA on outcomes in type 2 diabetes: A systematic review, meta-analysis, and real-world study from an international federated database

open access: yes
Aims. To evaluate the efficacy and cardiovascular outcomes of combination pioglitazone with either glucagon-like peptide 1 receptor agonist (GLP-1 RA) or sodium-glucose cotransporter-2 inhibitor (SGLT2i) in individuals with type 2 diabetes (T2D) by ...
Alam, Uazman   +7 more
core   +3 more sources

Effects of Glucagon-Like Peptide-1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors on Intima-Media Thickness: Systematic Review and Meta-Analysis

open access: yesJournal of Diabetes Research
Background. Beyond glycemic control, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT2is) have been proposed to reduce the risk of cardiovascular events.
Abolfazl Akbari   +2 more
doaj   +1 more source

Albuminuria and Serum Tumor Necrosis Factor Receptor Levels in Patients with Type 2 Diabetes on SGLT2 Inhibitors : A Prospective Study [PDF]

open access: yes
Introduction: Large-scale clinical trials of sodium-glucose cotransporter 2 inhibitors (SGLT2i) demonstrate proteinuria-reducing effects in diabetic kidney disease, even after treatment with renin–angiotensin inhibitors.
Aihara, Ken-ichi   +9 more
core  

Comparison of kidney and hepatic outcomes among sodium-glucose cotransporter-2 inhibitors: a retrospective study using multiple propensity scores

open access: yesJournal of Pharmaceutical Health Care and Sciences
Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have been reported to have effects beyond lowering blood glucose levels, with certain SGLT2i expanding their indications to chronic kidney disease and chronic heart failure.
Kazuya Hiura   +12 more
doaj   +1 more source

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