Results 1 to 10 of about 6,338 (167)

Zwitterionic Penicillin-Derived Sulfone Inhibitor for Combating β-Lactamase-Mediated Antibiotic Resistance. [PDF]

ChemMedChem
Combining enhanced permeability strategies with (2‐pyridyl)methylene substitution in the sulbactam scaffold led to a novel β‐lactamase inhibitor to combat β‐lactamase‐mediated resistance to β‐lactam antibiotics. The studies presented highlight the potential of compound 3 as a next‐generation β‐lactamase inhibitor for combating infections caused by ...
Rodríguez D, Lence E, Vázquez-Ucha JC, Beceiro A, González-Bello C.   +4 more
europepmc   +2 more sources

A Robust Heterometallic Pt₂Pd₂L₈ Double Cage Catenane. [PDF]

Angew Chem Int Ed Engl
The first heterometallic Pt(II)–Pd(II) quadruply interlocked cage catenane (Pt2Pd2L8) has been assembled via a combination of metal‐mediated self‐assembly and dynamic covalent chemistry. The integration of inert Pt(II) and labile Pd(II) ions within the architecture enables facile catenation while strongly enhancing stability of the assembly.
Ganta S, Mikherdov AS, Baksi A, Drechsler C, Clever GH.   +4 more
europepmc   +2 more sources

Empagliflozin-induced lipidome remodeling in type 2 diabetes: mechanistic insights and translational perspectives. [PDF]

Cardiovasc Diabetol
Izzo C, Carrizzo A.
europepmc   +1 more source

Design, rationale, and baseline characteristics of the dapagliflozin in haemodialysis (DAPA-HD) trial. [PDF]

ESC Heart Fail
Zelniker TA, Paschen C, Mann C, Eigner M, Hafner-Gießauf H, Kletzmayr J, Lorenz M, Ludvik B, Stulnig T, Waller I, Werzowa J, Hödlmoser S, Hengstenberg C, Oberbauer R, Hecking M.   +14 more
europepmc   +1 more source

Comprehensive Evaluation of 1H-Isoindole-1,3(2H)-Dione Derivatives: Pharmacokinetic Studies and Analgesic Potential in Various Pain Models. [PDF]

Int J Mol Sci
Dziubina A, Szkatuła D, Szczukowski Ł, Szafarz M, Rapacz A.   +4 more
europepmc   +1 more source

BPA Disrupts Hepatic Lipid and Carbohydrate Metabolism in Female Zebrafish: Protective Effects of Probiotics Revealed by FTIRI and Lipidomics. [PDF]

Int J Mol Sci
Giommi C, Santoni C, Carli F, Gastaldelli A, Maradonna F, Habibi HR, Giorgini E, Carnevali O.   +7 more
europepmc   +1 more source

Efficacy and safety of SGLT2 inhibitor on insulin resistance and hyperglycemia in Werner syndrome-A case report. [PDF]

J Diabetes Investig
Yagi T, Aotani D, Hasegawa C, Shimizu Y, Koyama H, Maezawa Y, Yokote K, Tanaka T.   +7 more
europepmc   +1 more source

Septic shock from urinary tract infection associated with sodium-glucose cotransporter 2 inhibitor in a high-risk patient with heart failure: A case report. [PDF]

J Int Med Res
Tang Y, Zhang Y, Liu X, Chen G, Yin L, Wu M.   +5 more
europepmc   +1 more source

Directed Evolution of an Efficient Polycarbonate Depolymerase With Exceptional Operational Stability. [PDF]

Angew Chem Int Ed Engl
Jones HA, Hutton AE, Harris-Jukes D, Davidson J, Johannissen LO, Levy CW, Shaver MP, Green AP.   +7 more
europepmc   +1 more source

Association between bisphenols A and the risk of endometriosis: results from an updated meta-analysis. [PDF]

Front Public Health
Chen Y, Wu J, Wang Y, Wang F, Yang Q, Zhu Y, Zhou Q, Sun C, Li P.   +8 more
europepmc   +1 more source