Results 31 to 40 of about 6,338 (167)

Gallium‐Catalyzed Tandem Carbonyl–Olefin Metathesis/Dehydrogenative Coupling Enables Rapid Access to Cyclopentenes

European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
A cationic gallium(III) catalyst enables rapid construction of substituted cyclopentenes via tandem carbonyl‐ene metathesis/Friedel–Crafts coupling. Electronic tuning of alcohol electrophiles allows access to diverse, densely functionalized rings in a single operation.
Arnaud Espied, Djamila Azrou, Alexandre Djurovic, Régis Guillot, Aurélien Alix, Vincent Gandon, Christophe Bour   +6 more
wiley   +1 more source

Brønsted Acid‐Catalyzed Direct N‐Alkylation of Anilines With Alcohols

ChemistrySelect, Volume 11, Issue 22, 11 June 2026.
Brønsted acid‐catalyzed methodology for the alkylation of anilines with alcohols has been developed. The reaction occurs in short reaction time with excellent functional group tolerance. A broad range of aniline and alcohol derivatives generates the desired adducts in good to excellent yields.
Rony Gantous, Yuri Bolshan
wiley   +1 more source

Synthesis of differently substitued benzhydryl diethyl phosphates [PDF]

, 2018
Zbog značajne uloge organofosfata u mnogim važnim fiziološkim procesima, do danas je osmišljeno više načina njihove sinteze. Za potrebe ovog rada sintetizirani su spojevi: 4,4'-dimetilbenzhidrilni dietil-fosfat, 4-metilbenzhidrilni dietil-fosfat, 4 ...
Gerić, Nicole
core  

A Gallium(I) β‐Amido‐Imino‐Phosphorane: A Five‐Membered N‐Heterocyclic Gallylene with Enhanced Nucleophilicity

ChemistryEurope, Volume 4, Issue 5, May 2026.
By introducing β‐amino‐imino‐phosphoranes (BAIPs) as a new class of strongly electron‐donating N,N’‐chelates, an N‐heterocyclic gallylene (NHGa) with enhanced nucleophilicity is obtained. The new NHGa is readily synthesized, and the ligand features potent 1H and 31P NMR probes for reaction control.
Aylin Nagel, Samuel R. Lawrence, Tobias Rüffer, Robert Kretschmer   +3 more
wiley   +1 more source

Synthesis and evaluation of 1-benzhydryl-sulfonyl-piperazine derivatives as inhibitors of tumor growth and tumor angiogenesis of mouse ehrlich ascites tumor in vivo

, 2008
A series of novel 1-benzhydryl-sulfonyl-piperazine derivatives 3(a-e) were synthesized by nucleophilic substitution reaction of 1-benzhydryl-piperazine with different sulfonyl chlorides and were characterized by 1H NMR, LC/MS, FTIR and elemental analysis.
Sharada, A. C., Chandru, H., Ananda Kumar, C. S., Karuna Kumar, M., Rangappa, K. S., Thimmegowda, N. R., Benaka Prasad, S. B.   +6 more
core   +1 more source

Development of potent dopamine-norepinephrine uptake inhibitors (DNRIs) based on a (2S,4R,5R)-2-benzhydryl-5-((4-methoxybenzyl)amino)tetrahydro-2H-pyran-4-ol molecular template

Bioorganic & Medicinal Chemistry, 2014
Current therapy of depression is less than ideal with remission rates of only 25–35% and response rates of 45–60%. It has been hypothesized that a dysfunctional dopaminergic system in the mesocorticolimbic pathway in depressive disorder may lead to ...
Soumava Santra, H. Sharma, S. Vedachalam, Tamara Antonio, M. Reith, Aloke K. Dutta   +5 more
semanticscholar   +1 more source

SYNTHESIS AND IN-VITRO STUDY OF NOVEL (Z)-1-BENZHYDRYL-4-CINNAMYLPIPERAZINE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS [PDF]

, 2015
Objective: The objective of this study was to synthesize Z- 1-benzhydryl-4-cinnamylpiperazines by novel stereo selective synthetic method and evaluation of their anticancer properties.Methods: A series of novel (Z)-1-benzhydryl-4-cinnamylpiperazine ...
Kiran, K. R., Diwakar, Latha, Shivaprakash, S., Reddy, Chandrasekara G   +3 more
core  

Synthesis of Novel 1-benzhydryl-4-(3-(piperidin-4-yl)propyl) Piperidine Sulfonamides as Anticonvulsant Agents

, 2010
A series of novel 1-benzhydryl-4-(3-(piperidin-4-yl)propyl)piperidine sulphonamide derivatives 8(a-j) was synthesized in good yield and met the structural requirements essential for anticonvulsant properties.
Prasanna, D. S., Ranganatha, S. R., Vinaya, K., Ananda Kumar, C. S., Veeresh, B., Rangappa, K. S., Patil, B. M., Benaka Prasad, S. B.   +7 more
core   +1 more source

Development of a Novel Polyleucine‐Based Immunopotentiator for Subunit Vaccines Against Group A Streptococcus

Small, Volume 22, Issue 22, 17 April 2026.
Self‐assembling amphiphilic peptide L15K6 is used as a novel immunoadjuvant for the development of a Group A Streptococcus vaccine. Robust antigen‐specific IgG responses are generated and manage to kill isolated strains of Group A Streptococcus. Cellular and bulk RNA sequencing data reveals that L15K6 regulates immune responses potentially through TLR ...
Lantian Lu, Jazmina L. Gonzalez Cruz, Rabina Giri, Yuexiao Zhang, Sahra Bashiri, Leslie C. Domínguez Cadena, Shuhang Li, Zeinab G. Khalil, Waleed M. Hussein, Jingwen Wang, Jolynn Kiong, Xuehan Lu, Jiahui Zhang, Miao Lu, Wenbin Huang, Wei Yang Kong, Ummey Jannatun Nahar, Prashamsa Koirala, Zhong Guo, Patricia Walden, Antje Blumenthal, Jakob Begun, Kirill Alexandrov, Istvan Toth, Rachel J. Stephenson, Mariusz Skwarczynski   +25 more
wiley   +1 more source

Tuning High Temperature Performance Through Targeted Halide Substitution in a Bis(Imino)Pyridine‐Iron Ethylene Polymerization Catalyst

Journal of Applied Polymer Science, Volume 143, Issue 11, March 15, 2026.
Through systematic developments in catalyst design, we report a series of exceptionally active on iron catalysts for the polymerization of ethylene that can run at high operating temperature forming highly linear polyethylene waxes with narrow dispersity and high levels of vinyl chain ends that could be influenced by the operating temperature.
Elizabeth Ogbe, Yanping Ma, Yizhou Wang, Gregory A. Solan, Qiuyue Zhang, Tongling Liang, Wen‐Hua Sun   +6 more
wiley   +1 more source