Results 21 to 30 of about 6,497 (154)

Development of a Novel Polyleucine‐Based Immunopotentiator for Subunit Vaccines Against Group A Streptococcus

Small, Volume 22, Issue 22, 17 April 2026.
Self‐assembling amphiphilic peptide L15K6 is used as a novel immunoadjuvant for the development of a Group A Streptococcus vaccine. Robust antigen‐specific IgG responses are generated and manage to kill isolated strains of Group A Streptococcus. Cellular and bulk RNA sequencing data reveals that L15K6 regulates immune responses potentially through TLR ...
Lantian Lu, Jazmina L. Gonzalez Cruz, Rabina Giri, Yuexiao Zhang, Sahra Bashiri, Leslie C. Domínguez Cadena, Shuhang Li, Zeinab G. Khalil, Waleed M. Hussein, Jingwen Wang, Jolynn Kiong, Xuehan Lu, Jiahui Zhang, Miao Lu, Wenbin Huang, Wei Yang Kong, Ummey Jannatun Nahar, Prashamsa Koirala, Zhong Guo, Patricia Walden, Antje Blumenthal, Jakob Begun, Kirill Alexandrov, Istvan Toth, Rachel J. Stephenson, Mariusz Skwarczynski   +25 more
wiley   +1 more source

Synthesis and Application of Bioactive N‐Functionalized Aziridines

Angewandte Chemie, Volume 137, Issue 44, October 27, 2025.
This review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Hao Tan, Samya Samanta, Nan Qiu, Alexander Adibekian, David C. Powers   +4 more
wiley   +2 more sources

Applications of the Conceptual Density Functional Theory Indices to Organic Chemistry Reactivity [PDF]

, 2016
Indexación: Web of ScienceTheoretical reactivity indices based on the conceptual Density Functional Theory (DFT) have become a powerful tool for the semiquantitative study of organic reactivity.
Domingo, Luis R., Pérez, Patricia, Ríos-Gutiérrez, Mar   +2 more
core   +2 more sources

Tuning High Temperature Performance Through Targeted Halide Substitution in a Bis(Imino)Pyridine‐Iron Ethylene Polymerization Catalyst

Journal of Applied Polymer Science, Volume 143, Issue 11, March 15, 2026.
Through systematic developments in catalyst design, we report a series of exceptionally active on iron catalysts for the polymerization of ethylene that can run at high operating temperature forming highly linear polyethylene waxes with narrow dispersity and high levels of vinyl chain ends that could be influenced by the operating temperature.
Elizabeth Ogbe, Yanping Ma, Yizhou Wang, Gregory A. Solan, Qiuyue Zhang, Tongling Liang, Wen‐Hua Sun   +6 more
wiley   +1 more source

Computational and Machine‐Learning Studies of Ethylene Oligomerization

Carbon and Hydrogen, Volume 28, Issue 1, Page 40-65, March 2026.
This review focuses on recent advances in computational and machine‐learning studies of ethylene oligomerization, highlighting mainstream catalyst systems based on Co, Ta, Ti, Zr, and Hf, with particular emphasis on Fe‐ and Cr‐based catalysts and their controlling factors governing reactivity and LAO distribution.
Zhixin Qin, Zhihui Song, Heying Feng, Li Jin   +3 more
wiley   +1 more source

Binuclear DOTA-based Gd(III) chelates: revisiting a straightforward strategy for relaxivity improvement [PDF]

, 2015
The need for MRI contrast agents with improved relaxivity maintains the development of new Gd(III) chelates an intensive and demanding field of research.
André, João P., Ferreira, Paula M. T., Fontes, André, Helm, Lothar, Karimi, Shima, Yulikovc, Maxim   +5 more
core   +1 more source

Novel solid-state emissive polymers and polymeric blends from a T-Shaped benzodifuran scaffold: A comparative study [PDF]

, 2020
Two novel polyimines were synthesized from a benzodifuran based diamino monomer and two dialdehydes bearing bulky groups and a flexible spacer. The polymers display tuned luminescence performance according to the presence of half-salen groups. The effect
Caruso, U., Diana, R., Panunzi, B., Tuzi, A.   +3 more
core   +1 more source

The Pentafluorophenyl Cation: A Superelectrophile and Diradical

Angewandte Chemie, Volume 137, Issue 39, September 22, 2025.
From radical to diradical cation. Photoionization (PI) of the thermally generated pentafluorophenyl radical yields the pentafluorophenyl cation in the gas phase. This cation is found to be a diradical with nearly degenerate open‐shell singlet and triplet ground states, and it is even more unstable than the parent phenyl cation by ∼40 kcal mol−1 ...
Enrique Mendez‐Vega, Adrián Portela‐González, Ginny Karir, Patrick Hemberger, Wolfram Sander   +4 more
wiley   +2 more sources

PEGylated DOTA-AHA-based Gd(III) chelates – A relaxometric study [PDF]

, 2015
Three PEGylated derivatives of 1,4,7,10-tetraazacyclododecane-1-((6-amino)hexanoic)-4,7,10-triacetic acid) (DOTA-AHA) with different molecular weights were prepared and characterized. Their Gd(III) chelates were studied in aqueous solution using variable-
André, João P., Ferreira, Paula M. T., Fontes, André, Helm, Lothar, Karimib, Shima   +4 more
core   +1 more source

Synthesis and evaluation of antimitotic activity of new tetralone acid analogues of podophyllotoxin [PDF]

, 2014
The new tetralone acids I (R = H, F, Me, OMe, SMe) were synthesized as analogs of podophyllotoxin. They were prepd. by replacing 3,4,5-trimethoxyphenyl ring with cyclohexyl group in podophyllotoxin and 1,3-methylene dioxy ring with methoxy, hydrogen, Me,
Basavaraju, Y. B., Krishna, M. H., Mallesha, N., Shivakumar, S. B., Umesha, B.   +4 more
core   +1 more source