Results 31 to 40 of about 61,487 (261)

Fault‐Tolerant Control Allocation for Overactuated Nonlinear Systems [PDF]

Asian Journal of Control, 2017
AbstractThis paper addresses the problem of fault‐tolerant control allocation for input affine nonlinear systems. The proposed scheme is divided in three main tasks: fault detection and estimation using a nonlinear observer, fault isolation through a bank of unknown input observers with a resetting policy to reduce the effects of nonlinearities and ...
Cristofaro, Andrea, Polycarpou, Marios M., Johansen, Tor Arne, Cristofaro, Andrea, Polycarpou, Marios M., Johansen, Tor Arne   +5 more
openaire   +5 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Determinants of Financial and Non-Financial Risk Tolerance among Students at Selected South African Universities

Foundations of Management, 2018
To enhance the portfolio allocation process, individuals need to understand their financial ability and psychological willingness to tolerate risks. To do this, their risk tolerance level must be quantified.
Ramudzuli Pfano Michael, Muzindutsi Paul-Francois   +1 more
doaj   +1 more source

Assertiveness and tolerance in cross-cultural interaction

Социальная психология и общество, 2017
The article is devoted to the theoretical analysis of the concepts of tolerance and assertiveness. Problem of contemporary cross-cultural interaction is the need to shift strategy of tolerance on strategy of assertiveness.
Pochebut L.G., Beznosov D.S.
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Inducible pesticide tolerance in Daphnia pulex influenced by resource availability

Ecology and Evolution, 2019
Pesticides are a ubiquitous contaminant in aquatic ecosystems. Despite the relative sensitivity of aquatic species to pesticides, growing evidence suggests that populations can respond to pesticides by evolving higher baseline tolerance or inducing a ...
Vanessa P. Wuerthner, Jared Jaeger, Paige S. Garramone, Connor O. Loomis, Yelena Pecheny, Rachel Reynolds, Lindsey Deluna, Samantha Klein, Michael Lam, Jessica Hua, George A. Meindl   +10 more
doaj   +1 more source

Comparative Genetic Diversity Analysis for Biomass Allocation and Drought Tolerance in Wheat

Agronomy, 2022
Genetic diversity is invaluable in developing climate-smart and drought-adapted wheat varieties. The aim of this study was to determine the extent of genetic variation present in wheat germplasm collections for biomass allocation and drought tolerance ...
Kwame W. Shamuyarira, Hussein Shimelis, Isack Mathew, Admire Shayanowako, Rebecca Zengeni, Vincent Chaplot   +5 more
doaj   +1 more source

Fault Tolerant Mechanism Design for General Task Allocation [PDF]

International Joint Conference on Autonomous Agents and Multiagent Systems, 2016
We study a general task allocation problem, involving multiple agents that collaboratively accomplish tasks and where agents may fail to successfully complete the tasks assigned to them (known as execution uncertainty). The goal is to choose an allocation that maximises social welfare while taking their execution uncertainty into account (i.e., fault ...
Zhao, Dengji, Ramchurn, Sarvapali, Jennings, Nicholas   +2 more
openaire   +3 more sources