Results 41 to 50 of about 302,221 (293)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Determinants of Financial and Non-Financial Risk Tolerance among Students at Selected South African Universities

open access: yesFoundations of Management, 2018
To enhance the portfolio allocation process, individuals need to understand their financial ability and psychological willingness to tolerate risks. To do this, their risk tolerance level must be quantified.
Ramudzuli Pfano Michael   +1 more
doaj   +1 more source

Assertiveness and tolerance in cross-cultural interaction

open access: yesСоциальная психология и общество, 2017
The article is devoted to the theoretical analysis of the concepts of tolerance and assertiveness. Problem of contemporary cross-cultural interaction is the need to shift strategy of tolerance on strategy of assertiveness.
Pochebut L.G., Beznosov D.S.
doaj   +1 more source

Constrained Fault-Tolerant Resource Allocation

open access: yes, 2012
In the Constrained Fault-Tolerant Resource Allocation (FTRA) problem, we are given a set of sites containing facilities as resources, and a set of clients accessing these resources. Specifically, each site i is allowed to open at most R_i facilities with cost f_i for each opened facility.
Liao, Kewen, Shen, Hong, Guo, Longkun
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Further Education Funding Council : circular : 99/47 : monitoring growth 1998-99 [PDF]

open access: yes, 1999
"Guidance on the monitoring of growth for 16 to 18 year olds and for widening participation" -- front ...

core  

Tolerance allocation using Monte Carlo simulation

open access: yesIOP Conference Series: Materials Science and Engineering, 2020
Abstract Tolerance allocation is an important issue in product manufacturing, ensuring on the one hand the interchangeability of parts in an assembly and on the other hand, it has a major impact on the costs of manufacturing products and quality.
A Tulcan, F V Banciu, I Grozav
openaire   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Inducible pesticide tolerance in Daphnia pulex influenced by resource availability

open access: yesEcology and Evolution, 2019
Pesticides are a ubiquitous contaminant in aquatic ecosystems. Despite the relative sensitivity of aquatic species to pesticides, growing evidence suggests that populations can respond to pesticides by evolving higher baseline tolerance or inducing a ...
Vanessa P. Wuerthner   +10 more
doaj   +1 more source

Comparative Genetic Diversity Analysis for Biomass Allocation and Drought Tolerance in Wheat

open access: yesAgronomy, 2022
Genetic diversity is invaluable in developing climate-smart and drought-adapted wheat varieties. The aim of this study was to determine the extent of genetic variation present in wheat germplasm collections for biomass allocation and drought tolerance ...
Kwame W. Shamuyarira   +5 more
doaj   +1 more source

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