Crosstalk tolerance analysis of coupled-line structures using least square-support vector machine technique. [PDF]
Sci Rep, 2023 Alijani MGH, Neshati MH.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Design of an Imaging Optical System for Large-Sized Stepped Shaft Diameter Detection
Applied SciencesAddressing the prevalent issues of low accuracy, low efficiency, and poor image quality in online diameter measurement of large-sized stepped shafts, this study introduces a novel method based on a symmetrical dual-telecentric optical path utilizing dual
Jie Duan +5 more
doaj +1 more source
Genome-wide identification, expression and salt stress tolerance analysis of the GRAS transcription factor family in Betula platyphylla. [PDF]
Front Plant Sci, 2022 He Z +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Fault Diagnostics and Tolerance Analysis of a Microgrid System Using Hamilton-Jacobi-Isaacs Equation and Game Theoretic Estimations in Sliding Mode Observers. [PDF]
Sensors (Basel), 2022 Shahzad E +6 more
europepmc +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Design of Off-Axis Four-Mirror Optical Systems Enabled by Freeform Optics
PhotonicsThe off-axis reflective optical system offers several advantages, including the elimination of central obstruction, zero chromatic aberration, and a compact structure. These features make it highly valuable in the domain of space remote sensing. Freeform
Jiadong Yu, Xianglong Mao
doaj +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source