Zero tolerance policing: new authoritarianism or new liberalism? [PDF]
, 2002 The notion of “zero tolerance” policing has been widely discussed in the media in recent years and has received considerable support from politicians right across the political spectrum both in the USA and the UK. Proponents of this apparently “get-tough”
Hopkins Burke, RD
core
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Machine learning approaches for predicting Cracking Tolerance Index (CTIndex) of asphalt concrete containing reclaimed asphalt pavement. [PDF]
PLoS One, 2023 Nguyen LN, Le TH, Nguyen LQ, Tran VQ.
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Air pollution tolerance index of Persea bombycina: Primary food plant of endemic muga silkworm (Antheraeaassamensis). [PDF]
Heliyon, 2023 Jigyasu DK +7 more
europepmc +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Cadmium-Induced Changes in the Accumulation of Sugars and the PsGolS Transcript in Pisum sativum L.
Applied SciencesCadmium (Cd) is a key stress factor that affects plant development. To examine the influence of Cd stress, we analysed the tissue localisation of polysaccharides (Periodic Acid Schiff reaction), qualitative and quantitative changes in soluble ...
Katarzyna Głowacka +5 more
doaj +1 more source
Selection of wheat (Triticum aestivum L.) genotypes under salt stress condition [PDF]
فیزیولوژی محیطی گیاهی, 2006 Wheat is a moderately tolerant plant to salinity stress, but its genotypes have difference in tolerance range in saline circumstance. In order to evaluate of breed wheat (Triticum aestivum L.) genotypes under saline and normal conditions, an experiment ...
Abbasali Nourinia
doaj
Yield-based drought tolerance index evaluates the drought tolerance of cotton germplasm lines in the interaction of genotype-by-environment. [PDF]
PeerJ, 2023 Sun F, Chen Q, Chen Q, Jiang M, Qu Y.
europepmc +1 more source