Results 111 to 120 of about 5,067,572 (306)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Efficient Fault-Tolerant Search by Fast Indexing of Subnetworks

open access: yesProceedings of the AAAI Conference on Artificial Intelligence
We design sensitivity oracles for error-prone networks. For a network problem Π, the data structure preprocesses a network G=(V,E) and sensitivity parameter f such that, for any set F of up to f link or node failures, it can report the solution of Π in G-F. We study three network problems Π.
Bilo' Davide   +4 more
openaire   +6 more sources

The evolutionary dynamics of tolerance [PDF]

open access: yes
This paper incorporates the phenomenon of tolerance, as the ability to accept diversity, into an economic analysis showing how different aptitudes to trust and cooperation can affect economic outcomes.
Di Dio, Fabio   +2 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Investigation and selection index for drought stress in durum wheat (Triticum durum Desf.) under Mediterranean condition [PDF]

open access: yesElectronic Journal of Plant Breeding, 2012
Drought is a wide-spread problem seriously influencing durum wheat (Triticum durum Desf.) production and quality, but development of resistant cultivars is hampered by the lack of effective selection criteria.
A.Guendouz* , S.Guessoum and M. Hafsi
doaj  

Salinity-Induced Physiological Changes in Pea (Pisum sativum L.): Germination Rate, Biomass Accumulation, Relative Water Content, Seedling Vigor and Salt Tolerance Index. [PDF]

open access: yesPlants (Basel), 2022
Khan MAH   +9 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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