Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex. [PDF]
Kuzikov M +13 more
europepmc +1 more source
The Use of Fluorescent Markers to Detect and Delineate Head and Neck Cancer: A Scoping Review. [PDF]
Srinivasan A, Kaminskaite V, Winter SC.
europepmc +1 more source
Exploring the photosensitizing potential of Nanoliposome Loaded Improved Toluidine Blue O (NLITBO) Against Streptococcus mutans: An in-vitro feasibility study. [PDF]
Panda S +6 more
europepmc +1 more source
Photoactivated disinfection procedure for denture stomatitis in diabetic rats. [PDF]
Zhang X +7 more
europepmc +1 more source
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Studies on tolonium chloride labeled with radioiodine
Journal of Radioanalytical and Nuclear Chemistry, 2010Tolonium chloride is a common reagent in the diagnosis of oral premalignant and malignant lesions. This study establishes the optimal preparation of radioiodinated tolonium chloride (RTC) and evaluate its radiochemical and biological characteristics. Instant thin layer chromatography (ITLC), ion exchange chromatography (IC), paper electrophoresis, and ...
Jiunn-Liang Lin +3 more
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Use of Tolonium Chloride in the Diagnosis of Malignant Gastric Ulcers
Archives of Surgery, 1978Peroral staining with tolonium chloride (toluidine blue) was performed in 45 patients with suspected gastric ulcer disease. During endoscopy, 19 of 21 malignant ulcers and one of 15 benign ulcers were stained. Following surgery, 18 of 21 malignant ulcers found in the surgical specimens were stained.
S, Giler, U, Kadish, I, Urca
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Use of meta-analysis to evaluate tolonium chloride in oral cancer screening
Oral Surgery, Oral Medicine, Oral Pathology, 1989This study used meta-analysis, an analytical technique that uses raw data from previous researchers, to estimate the efficacy of screening for oral cancer with tolonium chloride (TCl). TCl, a vital blue dye, selectively stains acid tissue components such as DNA and RNA and has been used for more than 20 years by surgeons to identify suspected cancerous
D, Rosenberg, S, Cretin
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Disinfection of clinical materials using photo-activated tolonium chloride solution
International Journal of Medical Engineering and Informatics, 2011Photo-activated disinfection is beginning to be used in dental surgery to treat deep seated bacterial infection. It works by combining a photosensitiser and light of a specific frequency to generate singlet oxygen which is toxic to many types of bacteria.
Thomson, G. A. +3 more
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Disinfection of Surgical Materials Using Photo-Activated Tolonium Chloride
2009Photo-activated disinfection is a technique which has recently become available for use in disinfection in dentistry. This technique makes use of the dye toluidine blue O coupled to a low powered laser to generate singlet oxygen which kills the bacteria without harming the patient.
Thomson, G. A. +3 more
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