Results 21 to 30 of about 74 (54)

Spatiotemporal Transcriptomic Atlas Reveals the Regulatory Mechanisms Underlying Early Inflorescence Development and Sex Differentiation in Spinach

Advanced Science, Volume 12, Issue 36, September 25, 2025.
High‐resolution spatiotemporal transcriptomic data from male and female spinach inflorescences across four key stages first reveal the sex differentiation initiates at the four‐leaf stage and is governed by epigenetic regulation via the SpMSI1‐SpHDT2 complex.
Chen You, Hao Yang, Yueyan Zhao, Xiaoning Wang, Shuaijie Wei, Ning Chen, Yulan Zhang, Luxian Liu, Wei Qian, Shufen Li, Wujun Gao   +10 more
wiley   +1 more source

Identification, validation, and characterization of approved and investigational drugs interfering with the SARS‐CoV‐2 endoribonuclease Nsp15

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Since the emergence of SARS‐CoV‐2 at the end of 2019, the virus has caused significant global health and economic disruptions. Despite the rapid development of antiviral vaccines and some approved treatments such as remdesivir and paxlovid, effective antiviral pharmacological treatments for COVID‐19 patients remain limited. This study explores
Spyros D. Chatziefthymiou, Maria Kuzikov, Sara Afandi, Greta Kovacs, Sukrit Srivastava, Andrea Zaliani, Andrey Gruzinov, Guillaume Pompidor, Michele Lunelli, Golam Rizvee Ahmed, Jörg Labahn, Johanna Hakanpää, Björn Windshügel, Michael Kolbe   +13 more
wiley   +1 more source

Medications and Acute Hemolysis in G6PD‐Deficient Patients – A Real‐World Study

Clinical Pharmacology &Therapeutics, Volume 116, Issue 6, Page 1537-1543, December 2024.
Many drug labels contain precautions of use in G6PD‐deficient patients due to hemolytic concerns, but much of this is based on scarce clinical, epidemiological, or structural data. In this real‐world study, we aimed to examine if the administration of presumably risky medications for G6PD‐deficient patients was followed by hemolysis. The study is based
Naomi Gronich, Bar Rosh, Nili Stein, Walid Saliba   +3 more
wiley   +1 more source

Mutations in CFAP47, a previously reported MMAF causative gene, also contribute to the respiratory defects in patients with PCD

Molecular Genetics &Genomic Medicine, Volume 12, Issue 1, January 2024.
We report two hemizygous CFAP47 variants in two independent PCD‐affected individuals. Our study proves that CFAP47 variants cause reduced numbers of cilia and misaligned basal bodies. The findings have important clinical implications for facilitating PCD diagnosis and genetic counseling.
Haijun Ge, Wangji Zhou, Miao He, Haixia Zheng, Xinyue Zhao, Ting Zhang, Ying Zhang, Chi Shao, Chongsheng Cheng, Yaping Liu, Xinlun Tian, Kai‐Feng Xu, Xue Zhang   +12 more
wiley   +1 more source

The strategy of three-dimensional Covalent Organic Frameworks to exclude dye contaminants in aqueous solutions

npj Clean Water
The development of effective solid adsorbents is necessary to remove organic pollutants from wastewater in response to the global water crisis.
Afsaneh Ghahari, Farzaneh Farzad, Reza Azadnejad   +2 more
doaj   +1 more source

Experience In The Use Of Photoactivated Disinfection Of Carious Cavities By Tolonium Chloride In The Treatment Of Deep Carious Lesions Of Dentin

, 2018
The prevalence of caries among the adult population of the Earth, according to WHO, exceeds 90% and, as a rule, teeth of the chewing group are primarily affected because of their anatomical structure. A pilot study of the use of photoactivated disinfection of carious cavities with a solution of tolonium chloride showed high efficiency in the prevention
Razumova S.N., Aymaletdinova Z.T., Ivanova E.V., Saleeva G.T., Saleev R.D.   +4 more
openaire   +4 more sources

Degradation of Tolonium Chloride Dye by Phosphate Ion in Aqueous Acidic Solution: Kinetic Approach

Journal of the Turkish Chemical Society Section A: Chemistry
The degradation of tolonium chloride (TC+) dye by phosphate ion (PO43-) in an aqueous acidic solution was studied using spectrophotometric analysis at 301 K, I= 1.0 M, [TC+]= 1.5 × 10-5 M, [H+]= 1.0×10-3 M, and ʎmax 600 nm. To determine the potency and rate of the reactant species, an aqueous acidic medium was employed.
Patricia Umoru, Mohammad Lawal, Oluwayemisi Abiodun Babatunde, Yusuf Sahabı   +3 more
openaire   +2 more sources

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Studies on tolonium chloride labeled with radioiodine

Journal of Radioanalytical and Nuclear Chemistry, 2010
Tolonium chloride is a common reagent in the diagnosis of oral premalignant and malignant lesions. This study establishes the optimal preparation of radioiodinated tolonium chloride (RTC) and evaluate its radiochemical and biological characteristics. Instant thin layer chromatography (ITLC), ion exchange chromatography (IC), paper electrophoresis, and ...
Ren-Shyan Liu, Jiunn-Guang Lo, Liu Ren-Shyan   +2 more
exaly   +3 more sources

Use of Tolonium Chloride in the Diagnosis of Malignant Gastric Ulcers

Archives of Surgery, 1978
Peroral staining with tolonium chloride (toluidine blue) was performed in 45 patients with suspected gastric ulcer disease. During endoscopy, 19 of 21 malignant ulcers and one of 15 benign ulcers were stained. Following surgery, 18 of 21 malignant ulcers found in the surgical specimens were stained.
I Urca
exaly   +3 more sources

Disinfection of clinical materials using photo-activated tolonium chloride solution

International Journal of Medical Engineering and Informatics, 2011
Photo-activated disinfection is beginning to be used in dental surgery to treat deep seated bacterial infection. It works by combining a photosensitiser and light of a specific frequency to generate singlet oxygen which is toxic to many types of bacteria.
Gareth A. Thomson, Mark S. Pridham, Yunli Liu, Ruth E. Mackay   +3 more
exaly   +3 more sources