Results 121 to 130 of about 676 (165)
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Veterinary Parasitology, 2010
The objective of this study was to evaluate the pharmacokinetic profiles of toltrazuril (TZR), and its major metabolites toltrazuril sulfoxide (TZR x SO) and toltrazuril sulfone (TZR x SO(2)) in rabbits after oral administrations. Rabbits were dosed once with 10 and 20mg/kg TZR via stomach tube with manual restraint.
J Lim, Youn-Hwan Hwang, Hyo-In Yun
exaly +3 more sources
The objective of this study was to evaluate the pharmacokinetic profiles of toltrazuril (TZR), and its major metabolites toltrazuril sulfoxide (TZR x SO) and toltrazuril sulfone (TZR x SO(2)) in rabbits after oral administrations. Rabbits were dosed once with 10 and 20mg/kg TZR via stomach tube with manual restraint.
J Lim, Youn-Hwan Hwang, Hyo-In Yun
exaly +3 more sources
Journal of Veterinary Pharmacology and Therapeutics, 2023
AbstractToltrazuril (TZR) is currently the only registered chemotherapeutic drug in the European Union for the treatment of Cystoisospora suis. This study investigated the comparative pharmacokinetics and tissue concentration‐time profiles of TZR and its active metabolite, toltrazuril sulfone (TZR‐SO2), after oral (per os, p.o.) and intramuscular (i.m.)
Ta‐Wei Yeh +6 more
openaire +2 more sources
AbstractToltrazuril (TZR) is currently the only registered chemotherapeutic drug in the European Union for the treatment of Cystoisospora suis. This study investigated the comparative pharmacokinetics and tissue concentration‐time profiles of TZR and its active metabolite, toltrazuril sulfone (TZR‐SO2), after oral (per os, p.o.) and intramuscular (i.m.)
Ta‐Wei Yeh +6 more
openaire +2 more sources
Migration and toxicity of toltrazuril and its main metabolites in the environment
Chemosphere, 2022Veterinary drugs heavily used in livestock are passed into the environment through different ways, resulting in risks to terrestrial environments and humans. The migration of toltrazuril (TOL), an important anticoccidial drug used intensively in livestock, and its main metabolites between the chicken manure compost, soil and vegetables was investigated,
Meixia Huo +5 more
openaire +2 more sources
Solubility of Toltrazuril and the Effect of a Cosolvent
Journal of Chemical & Engineering Data, 2018The purpose of this work is to study the dissolution process of toltrazuril and the influence of the solvent on solubility.
Yüfang Wu +3 more
openaire +1 more source
Deposition and depletion of the coccidiostats toltrazuril and halofuginone in eggs
Analytica Chimica Acta, 2005Abstract Toltrazuril (TZ), a triazinetrione derivative, and halofuginone (HFG), a quinazolinone derivative, have been licensed for the prevention and treatment of coccidiosis in broilers and turkeys, but have been excluded for use in laying hens. Little is known regarding the deposition of residues of toltrazuril and halofuginone in eggs and their ...
Björn J A Berendsen, J A Van Rhijn
exaly +3 more sources
Efficacy of toltrazuril against intestinal and hepatic coccidiosis in rabbits
Veterinary Parasitology, 1986The anticoccidial effect of toltrazuril (Bay Vi 9142) against Eimeria flavescens, E. intestinalis, E. magna, E. perforans and E. stiedai was tested in experimentally-infected rabbits. Continuous administration of 10-15 p.p.m. of the drug in the drinking water was highly effective in reducing oocyst output of all five species and in preventing clinical ...
J E, Peeters, R, Geeroms
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Experimental Treatment of Hepatozoon Infections with the Anticoccidial Agent Toltrazuril
Journal of Veterinary Medicine, Series B, 1988SummaryA new in vivo test model for experimental anticoccidial drug research has been developed. Hepatozoon erhardovae, a very common flea‐borne hemogregarine species of the European bank vole, causes lethal infections when sufficient sporozoites are administered.
H E, Krampitz, A, Haberkorn
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Chemoprophylaxis of coccidiosis in lambs with a single oral dose of toltrazuril
Veterinary Parasitology, 1991The prophylactic efficacy of a single oral dose of toltrazuril against coccidiosis (mixed Eimeria infections) in naturally infected lambs was evaluated in two experiments. Toltrazuril at 20 mg kg-1, given on Day 7 or Day 10 after turnout on pasture, proved to be highly efficacious in preventing clinical coccidiosis under Norwegian conditions ...
B, Gjerde, O, Helle
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Avian Diseases, 2003
A 42-day broiler floor pen study was conducted comparing the anticoccidial efficacy of toltrazuril (Baycox) as a stand alone treatment and as an additional treatment to in-feed anticoccidial programs. Toltrazuril was administered on days 18 and 19 in the drinking water at 7 mg/kg of body weight.
G F Mathis
exaly +3 more sources
A 42-day broiler floor pen study was conducted comparing the anticoccidial efficacy of toltrazuril (Baycox) as a stand alone treatment and as an additional treatment to in-feed anticoccidial programs. Toltrazuril was administered on days 18 and 19 in the drinking water at 7 mg/kg of body weight.
G F Mathis
exaly +3 more sources
The use of toltrazuril for the prevention of coccidiosis in piglets before weaning
Australian Veterinary Journal, 1995SUMMARY:To determine the efficacy of toltrazuril as a prophylactic treatment for coccidiosis in piglets caused byIsospora suis (I suis), a single 1.0 mL dose of toltrazuril was administered orally to 1056 piglets between 3 and 6 days of age, in 5 piggeries.
S J, Driesen, V A, Fahy, P G, Carland
openaire +2 more sources