Absorption and Distribution of Toltrazuril and Toltrazuril Sulfone in Plasma, Intestinal Tissues and Content of Piglets after Oral or Intramuscular Administration [PDF]
Molecules, 2021 Piglet coccidiosis due to Cystoisospora suis is a major cause of diarrhea and poor growth worldwide. It can effectively be controlled by application of toltrazuril (TZ), and oral formulations have been licensed for many years.
Hamadi Karembe +9 more
doaj +3 more sources
Journal of Veterinary Pharmacology and Therapeutics, Volume 47, Issue 6, Page 492-502, November 2024.Abstract Iron deficiency anemia (IDA) and cystoisosporosis are the most common clinical conditions of fast‐growing piglets. Until now, IDA and cystoisosporosis have been managed by intramuscular injection of iron complexes (such as dextran or gleptoferron) and oral administration of toltrazuril.
Hamadi Karembe +8 more
wiley +3 more sources
Experimentally confirmed toltrazuril resistance in a field isolate of Cystoisospora suis [PDF]
Parasites & Vectors, 2017 Background Constant treatment regimens with toltrazuril against Cystoisospora suis infection in piglets are being applied in the intensive production systems for the last two decades, but the possibility of resistance development has not been addressed ...
Aruna Shrestha +5 more
doaj +3 more sources
Efficacy of injectable toltrazuril-iron combination product and oral toltrazuril against early experimental infection of suckling piglets with Cystoisospora suis [PDF]
Parasites & Vectors, 2019 Background Toltrazuril is frequently administered for the metaphylactic control of piglet cystoisosporosis. In a previous study, the efficacy of parenteral toltrazuril (45 mg/piglet, Group Forceris®) applied on the 2nd day of life (dol), and of oral ...
Anja Joachim +6 more
doaj +3 more sources
Effect of Isosporiasis Prevention with Toltrazuril on Long-Term Pig Performance [PDF]
The Scientific World Journal, 2012 The efficacy of toltrazuril treatment was assessed in two experiments in Polish swine herds. Experiment 1 included a toltrazuril treatment group, Group A (n=410), and untreated control, Group B (n=386).
K. Rypula +4 more
doaj +3 more sources
Comparison of an injectable toltrazuril-gleptoferron (Forceris®) and an oral toltrazuril (Baycox®) + injectable iron dextran for the control of experimentally induced piglet cystoisosporosis [PDF]
Parasites & Vectors, 2018 Background Cystoisospora suis causes diarrhoeal disease and reduced weight gain in suckling piglets, and a toltrazuril-based oral suspension is available for treatment.
Anja Joachim +6 more
doaj +3 more sources
Cytotoxicity and Antiparasitic Effects of Toltrazuril Against Enteromyxum leei in Olive Flounders: In Vitro and In Vivo Analyses. [PDF]
J Fish DisABSTRACT The parasite Enteromyxum leei causes serious emaciation disease in marine fish species. Toltrazuril exhibits antiparasitic effects; however, the simultaneous impacts of toltrazuril on parasites and hosts are unclear. Here, we evaluate the cytotoxicity of three commercial toltrazuril products (A, B and C) and the treatment efficacy against E ...
Lee YJ, Oh YE, Lee EJ, Jun LJ, Jeong JB.
europepmc +2 more sources
The efficacy of toltrazuril for prevention of oriental theileriosis (Theileria orientalis Ikeda genotype) in Friesian calves. [PDF]
Aust Vet JThe aim of this non‐blinded, randomised, controlled study was to determine the efficacy of toltrazuril for the prevention of oriental theileriosis in calves. Thirty calves were infected with Theileria orientalis Ikeda genotype through the application and retention of infected female bush ticks (Haemaphysalis longicornis). 15 Group 1 calves were treated
de Burgh SG, Emery DL.
europepmc +2 more sources
Pharmacokinetics of toltrazuril and its metabolites toltrazuril sulphoxide and toltrazuril sulphone in pregnant and non-pregnant goats [PDF]
Acta Veterinaria Brno, 2021 The pharmacokinetic characteristics of toltrazuril (TZR) and its metabolites toltrazuril sulphoxide (TZR.SO) and toltrazuril sulphone (TZR.SO 2 ) were assessed in non-pregnant and pregnant goats.
Sara T. Elazab +2 more
openaire +1 more source
The efficiency of toltrazuril, thymol, and toltrazuril + thymol combination on eimeriosis in lamb
Turkish Journal of Veterinary & Animal Sciences, 2023 This study aimed to evaluate and compare the efficacy of the treatment with a single dose of toltrazuril 5% (Baycox), thymol (Versatile, Nine Life, United Arab Emirates), and toltrazuril + thymol combination to control Eimeria spp. infection in lambs in intensive feeding.
Candar, Ali Erdi +5 more
openaire +3 more sources